Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AAO56651.1Conserved domain protein; Similar to SP:P37691, PID:912478, GB:U00096, and PID:1790043; identified by sequence similarity; putative. (320 aa)    
Predicted Functional Partners:
hrpW1
Type III helper protein HrpW1; Similar to GP:3694999, and GP:8037796; identified by sequence similarity; putative; see PMID:20190049 for expression data; similar to GP:3694999, and GP:8037796, identified by sequence similarity, putative.
  
    0.705
phcA
PhcA; See PMID: 18363647; similar to GP:14029167, and GP:14029167; identified by sequence similarity; putative.
  
     0.592
AAO57967.1
This gene is aparrently the terminal component of a non-ribosomal peptide synthetase (due to the presence of the terminal thioesterase domain) and is most likely associated with the previous gene which appears to be a initiating component. This gene contains three complete amino acid activation, thiolation and condensation domain modules and appears to be specific for glycine, an unidentified amino acid and serine according to the prediction algorithm at http://raynam.chm.jhu.edu/; nrps/index2.html. Taken together these two genes appear to direct the biosynthesis of a previously undesc [...]
 
  
 0.562
AAO56148.1
FAD-binding monooxygenase, PheA/TfdB family; Similar to GP:11544755, and SP:P42535; identified by sequence similarity; putative.
  
     0.560
mucA
Sigma factor algU negative regulatory protein MucA; See PMID:20190049 for expression data; similar to SP:P38107; identified by sequence similarity; putative.
  
 
 0.557
AAO56650.1
Lipoprotein, putative; Similar to GP:13937482; identified by sequence similarity; putative.
       0.545
cmaA
Coronamic acid synthetase CmaA; Non-ribosomal peptide synthetase with adenylation and thiolation domains; reacts with the AMP derivative of L-allo-isoleucine to produce an aminoacyl thiolester intermediate during coronamic acid biosynthesis; see PMID: 14679222; see PMID:20190049 for expression data; non-ribosomal peptide synthetase with adenylation and thiolation domains, reacts with the AMP derivative of L-allo-isoleucine to produce an aminoacyl thiolester intermediate during coronamic acid biosynthesis, see PMID: 14679222.
 
  
 0.528
AAO53844.1
Monooxygenase; Similar to GP:5763911; identified by sequence similarity; putative.
  
     0.506
cfa6
Coronafacic acid polyketide synthase I; This gene is the first of two multimodular polyketide synthetases involved in the biosynthesis of coronafacic acid. This synthetase is proposed to receive CPC (2-carboxy-2-cyclopentenone) from an acyl carrier protein (cfa1), it then adds a buyrate group and then completely reduces the ketone of the (former) carboxylate group. The resulting product is then passed to the second polyketide synthetase (cfa7); similar to GP:13346874; identified by sequence similarity; putative; see PMID:20190049 for expression data; This gene is the first of two multi [...]
 
   
 0.505
hopAK1
Type III helper protein HopAK1; Previously known as HopPmaH (PMID11872842; Guttman et al, 2002); similar to GP:1783275, and GP:19071494; identified by sequence similarity; putative.
  
     0.482
Your Current Organism:
Pseudomonas syringae tomato
NCBI taxonomy Id: 223283
Other names: P. syringae pv. tomato str. DC3000, Pseudomonas syringae DC3000, Pseudomonas syringae pv. tomato DC3000, Pseudomonas syringae pv. tomato str. ATCC BAA-871, Pseudomonas syringae pv. tomato str. DC3000
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