Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
cobIPrecorrin-2 C20-methyltransferase; Methylates precorrin-2 at the C-20 position to produce precorrin-3A. (243 aa)    
Predicted Functional Partners:
AAO58303.1
CbiG protein/precorrin-3B C17-methyltransferase; See PMID:20190049 for expression data.
 
 0.999
cobH
precorrin-8X methylmutase; See PMID:20190049 for expression data.
  
 0.996
AAO58306.1
Cobalamin biosynthesis protein CobG, putative; See PMID:20190049 for expression data.
 
 
 0.991
AAO58309.1
Precorrin-6x reductase, putative.
 
  
 0.984
cobL
precorrin-6Y C5,15-methyltransferase (decarboxylating); See PMID:20190049 for expression data.
 
  
 0.978
cbiD
Cobalamin biosynthesis protein CbiD; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
 
  
 0.962
cysG
Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.
 
  
 0.952
cobA
uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family.
 
 
 0.933
AAO53684.1
uroporphyrin-III C-methyltransferase, putative; See PMID:20190049 for expression data.
     
  0.900
cobB
Cobyrinic acid a,c-diamide synthase family protein; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.
 
  
 0.830
Your Current Organism:
Pseudomonas syringae tomato
NCBI taxonomy Id: 223283
Other names: P. syringae pv. tomato str. DC3000, Pseudomonas syringae DC3000, Pseudomonas syringae pv. tomato DC3000, Pseudomonas syringae pv. tomato str. ATCC BAA-871, Pseudomonas syringae pv. tomato str. DC3000
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