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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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glnEGlutamate-ammonia-ligase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transd [...] (985 aa)    
Predicted Functional Partners:
glnD
[protein-pII] uridylyltransferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
 
   
 0.877
waaC
Lipopolysaccharide heptosyltransferase; See PMID:20190049 for expression data; similar to SP:P24173; identified by sequence similarity; putative.
      0.840
AAO58426.1
Lipopolysaccharide biosynthesis protein, putative; See PMID:20190049 for expression data; similar to GP:4323000; identified by sequence similarity; putative.
       0.751
AAO58427.1
Lipopolysaccharide core biosynthesis protein, putative; See PMID:20190049 for expression data; similar to GP:3482880; identified by sequence similarity; putative.
       0.751
waaP
Lipopolysaccharide core biosynthesis protein WaaP; Catalyzes the phosphorylation of heptose(I) of the outer membrane lipopolysaccharide core; Belongs to the protein kinase superfamily. KdkA/rfaP family.
       0.751
waaG
Lipopolysaccharide core biosynthesis protein WaaG; See PMID:20190049 for expression data; similar to GB:X55137; identified by sequence similarity; putative.
       0.751
rfaF
ADP-heptose--LPS heptosyltransferase II; See PMID:20190049 for expression data; similar to SP:P37692, GB:U14003, SP:P39352, PID:537120, GB:U00096, and PID:1790730; identified by sequence similarity; putative.
       0.751
AAO58425.1
Conserved protein of unknown function; See PMID:20190049 for expression data; identified by Glimmer.
       0.725
glnA-1
Glutamine synthetase, type I; Identified by match to TIGR protein family HMM TIGR01692; see PMID:20190049 for expression data; identified by match to TIGR protein family HMM TIGR01692.
 
   
 0.674
AAO54015.1
Nucleotidyltransferase, putative; See PMID:20190049 for expression data.
      
 0.638
Your Current Organism:
Pseudomonas syringae tomato
NCBI taxonomy Id: 223283
Other names: P. syringae pv. tomato str. DC3000, Pseudomonas syringae DC3000, Pseudomonas syringae pv. tomato DC3000, Pseudomonas syringae pv. tomato str. ATCC BAA-871, Pseudomonas syringae pv. tomato str. DC3000
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