| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| folB-1 | folC | PSPTO_0542 | PSPTO_3814 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Folylpolyglutamate synthase/dihydrofolate synthase; Similar to GP:146009, and SP:P08192; identified by sequence similarity; putative; see PMID:20190049 for expression data; similar to GP:146009, and SP:P0819, identified by sequence similarity, putative; Belongs to the folylpolyglutamate synthase family. | 0.762 |
| folB-1 | folE-1 | PSPTO_0542 | PSPTO_1182 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | GTP cyclohydrolase I; See PMID:20190049 for expression data; identified by match to PFAM protein family HMM PF01227. | 0.725 |
| folB-1 | folE-2 | PSPTO_0542 | PSPTO_2035 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | GTP cyclohydrolase I; See PMID:20190049 for expression data. | 0.725 |
| folB-1 | folK-1 | PSPTO_0542 | PSPTO_0543 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase. | 0.997 |
| folB-1 | folK-2 | PSPTO_0542 | PSPTO_0962 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; See PMID:20190049 for expression data; similar to GP:3970811, and SP:P26281; identified by sequence similarity; putative. | 0.988 |
| folB-1 | folP | PSPTO_0542 | PSPTO_4496 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.992 |
| folB-1 | pabC | PSPTO_0542 | PSPTO_3829 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 4-amino-4-deoxychorismate lyase; See PMID:20190049 for expression data; similar to SP:P28305, GB:X68505, GB:X68505, GB:X63381, GB:X63381, SP:Q02078, SP:Q02080, PID:1197538, PID:34536, and PID:432656; identified by sequence similarity; putative. | 0.458 |
| folC | folB-1 | PSPTO_3814 | PSPTO_0542 | Folylpolyglutamate synthase/dihydrofolate synthase; Similar to GP:146009, and SP:P08192; identified by sequence similarity; putative; see PMID:20190049 for expression data; similar to GP:146009, and SP:P0819, identified by sequence similarity, putative; Belongs to the folylpolyglutamate synthase family. | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.762 |
| folC | folE-1 | PSPTO_3814 | PSPTO_1182 | Folylpolyglutamate synthase/dihydrofolate synthase; Similar to GP:146009, and SP:P08192; identified by sequence similarity; putative; see PMID:20190049 for expression data; similar to GP:146009, and SP:P0819, identified by sequence similarity, putative; Belongs to the folylpolyglutamate synthase family. | GTP cyclohydrolase I; See PMID:20190049 for expression data; identified by match to PFAM protein family HMM PF01227. | 0.561 |
| folC | folE-2 | PSPTO_3814 | PSPTO_2035 | Folylpolyglutamate synthase/dihydrofolate synthase; Similar to GP:146009, and SP:P08192; identified by sequence similarity; putative; see PMID:20190049 for expression data; similar to GP:146009, and SP:P0819, identified by sequence similarity, putative; Belongs to the folylpolyglutamate synthase family. | GTP cyclohydrolase I; See PMID:20190049 for expression data. | 0.561 |
| folC | folK-1 | PSPTO_3814 | PSPTO_0543 | Folylpolyglutamate synthase/dihydrofolate synthase; Similar to GP:146009, and SP:P08192; identified by sequence similarity; putative; see PMID:20190049 for expression data; similar to GP:146009, and SP:P0819, identified by sequence similarity, putative; Belongs to the folylpolyglutamate synthase family. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase. | 0.480 |
| folC | folK-2 | PSPTO_3814 | PSPTO_0962 | Folylpolyglutamate synthase/dihydrofolate synthase; Similar to GP:146009, and SP:P08192; identified by sequence similarity; putative; see PMID:20190049 for expression data; similar to GP:146009, and SP:P0819, identified by sequence similarity, putative; Belongs to the folylpolyglutamate synthase family. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; See PMID:20190049 for expression data; similar to GP:3970811, and SP:P26281; identified by sequence similarity; putative. | 0.797 |
| folC | folP | PSPTO_3814 | PSPTO_4496 | Folylpolyglutamate synthase/dihydrofolate synthase; Similar to GP:146009, and SP:P08192; identified by sequence similarity; putative; see PMID:20190049 for expression data; similar to GP:146009, and SP:P0819, identified by sequence similarity, putative; Belongs to the folylpolyglutamate synthase family. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.998 |
| folC | nuoCD | PSPTO_3814 | PSPTO_3367 | Folylpolyglutamate synthase/dihydrofolate synthase; Similar to GP:146009, and SP:P08192; identified by sequence similarity; putative; see PMID:20190049 for expression data; similar to GP:146009, and SP:P0819, identified by sequence similarity, putative; Belongs to the folylpolyglutamate synthase family. | NADH dehydrogenase I, C/D subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the N-terminal section; belongs to the complex I 30 kDa subunit family. | 0.508 |
| folE-1 | folB-1 | PSPTO_1182 | PSPTO_0542 | GTP cyclohydrolase I; See PMID:20190049 for expression data; identified by match to PFAM protein family HMM PF01227. | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.725 |
| folE-1 | folC | PSPTO_1182 | PSPTO_3814 | GTP cyclohydrolase I; See PMID:20190049 for expression data; identified by match to PFAM protein family HMM PF01227. | Folylpolyglutamate synthase/dihydrofolate synthase; Similar to GP:146009, and SP:P08192; identified by sequence similarity; putative; see PMID:20190049 for expression data; similar to GP:146009, and SP:P0819, identified by sequence similarity, putative; Belongs to the folylpolyglutamate synthase family. | 0.561 |
| folE-1 | folE-2 | PSPTO_1182 | PSPTO_2035 | GTP cyclohydrolase I; See PMID:20190049 for expression data; identified by match to PFAM protein family HMM PF01227. | GTP cyclohydrolase I; See PMID:20190049 for expression data. | 0.901 |
| folE-1 | folK-1 | PSPTO_1182 | PSPTO_0543 | GTP cyclohydrolase I; See PMID:20190049 for expression data; identified by match to PFAM protein family HMM PF01227. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase. | 0.630 |
| folE-1 | folK-2 | PSPTO_1182 | PSPTO_0962 | GTP cyclohydrolase I; See PMID:20190049 for expression data; identified by match to PFAM protein family HMM PF01227. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; See PMID:20190049 for expression data; similar to GP:3970811, and SP:P26281; identified by sequence similarity; putative. | 0.916 |
| folE-1 | folP | PSPTO_1182 | PSPTO_4496 | GTP cyclohydrolase I; See PMID:20190049 for expression data; identified by match to PFAM protein family HMM PF01227. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.897 |