node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AAO54943.1 | AAO54949.1 | PSPTO_1422 | PSPTO_1428 | Rrf2 family protein; Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins. | Ferredoxin, 2Fe-2S; See PMID:20190049 for expression data. | 0.750 |
AAO54943.1 | AAO54950.1 | PSPTO_1422 | PSPTO_1429 | Rrf2 family protein; Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins. | Conserved protein of unknown function; See PMID:20190049 for expression data. | 0.648 |
AAO54943.1 | hscA | PSPTO_1422 | PSPTO_1427 | Rrf2 family protein; Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins. | Chaperone protein HscA; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. | 0.562 |
AAO54943.1 | hscB | PSPTO_1422 | PSPTO_1426 | Rrf2 family protein; Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins. | Co-chaperone Hsc20; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family. | 0.915 |
AAO54943.1 | iscA | PSPTO_1422 | PSPTO_1425 | Rrf2 family protein; Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins. | Iron-binding protein IscA; Is able to transfer iron-sulfur clusters to apo-ferredoxin. Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system; Belongs to the HesB/IscA family. | 0.795 |
AAO54943.1 | iscS-2 | PSPTO_1422 | PSPTO_1423 | Rrf2 family protein; Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins. | Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily. | 0.894 |
AAO54943.1 | iscS-3 | PSPTO_1422 | PSPTO_3438 | Rrf2 family protein; Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins. | Cysteine desulfurase; See PMID:20190049 for expression data; similar to SP:P39171, GB:D90244, and PID:216809; identified by sequence similarity; putative. | 0.662 |
AAO54943.1 | iscU | PSPTO_1422 | PSPTO_1424 | Rrf2 family protein; Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins. | Iron-binding protein IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | 0.964 |
AAO54949.1 | AAO54943.1 | PSPTO_1428 | PSPTO_1422 | Ferredoxin, 2Fe-2S; See PMID:20190049 for expression data. | Rrf2 family protein; Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins. | 0.750 |
AAO54949.1 | AAO54950.1 | PSPTO_1428 | PSPTO_1429 | Ferredoxin, 2Fe-2S; See PMID:20190049 for expression data. | Conserved protein of unknown function; See PMID:20190049 for expression data. | 0.994 |
AAO54949.1 | cyaY | PSPTO_1428 | PSPTO_0227 | Ferredoxin, 2Fe-2S; See PMID:20190049 for expression data. | cyaY protein; Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis. | 0.847 |
AAO54949.1 | dnaK | PSPTO_1428 | PSPTO_4505 | Ferredoxin, 2Fe-2S; See PMID:20190049 for expression data. | dnaK protein; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.542 |
AAO54949.1 | hscA | PSPTO_1428 | PSPTO_1427 | Ferredoxin, 2Fe-2S; See PMID:20190049 for expression data. | Chaperone protein HscA; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. | 0.983 |
AAO54949.1 | hscB | PSPTO_1428 | PSPTO_1426 | Ferredoxin, 2Fe-2S; See PMID:20190049 for expression data. | Co-chaperone Hsc20; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family. | 0.986 |
AAO54949.1 | iscA | PSPTO_1428 | PSPTO_1425 | Ferredoxin, 2Fe-2S; See PMID:20190049 for expression data. | Iron-binding protein IscA; Is able to transfer iron-sulfur clusters to apo-ferredoxin. Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system; Belongs to the HesB/IscA family. | 0.961 |
AAO54949.1 | iscS-2 | PSPTO_1428 | PSPTO_1423 | Ferredoxin, 2Fe-2S; See PMID:20190049 for expression data. | Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily. | 0.943 |
AAO54949.1 | iscS-3 | PSPTO_1428 | PSPTO_3438 | Ferredoxin, 2Fe-2S; See PMID:20190049 for expression data. | Cysteine desulfurase; See PMID:20190049 for expression data; similar to SP:P39171, GB:D90244, and PID:216809; identified by sequence similarity; putative. | 0.851 |
AAO54949.1 | iscU | PSPTO_1428 | PSPTO_1424 | Ferredoxin, 2Fe-2S; See PMID:20190049 for expression data. | Iron-binding protein IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | 0.987 |
AAO54950.1 | AAO54943.1 | PSPTO_1429 | PSPTO_1422 | Conserved protein of unknown function; See PMID:20190049 for expression data. | Rrf2 family protein; Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins. | 0.648 |
AAO54950.1 | AAO54949.1 | PSPTO_1429 | PSPTO_1428 | Conserved protein of unknown function; See PMID:20190049 for expression data. | Ferredoxin, 2Fe-2S; See PMID:20190049 for expression data. | 0.994 |