node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AAO56456.1 | fmt | PSPTO_2964 | PSPTO_0178 | Conserved hypothetical protein; Similar to GP:17431911; identified by sequence similarity; putative; Belongs to the class-I aminoacyl-tRNA synthetase family. | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | 0.919 |
AAO56456.1 | ileS | PSPTO_2964 | PSPTO_0806 | Conserved hypothetical protein; Similar to GP:17431911; identified by sequence similarity; putative; Belongs to the class-I aminoacyl-tRNA synthetase family. | isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. | 0.778 |
AAO56456.1 | leuS | PSPTO_2964 | PSPTO_4812 | Conserved hypothetical protein; Similar to GP:17431911; identified by sequence similarity; putative; Belongs to the class-I aminoacyl-tRNA synthetase family. | leucyl-tRNA synthetase; See PMID:20190049 for expression data; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.815 |
AAO56456.1 | metE | PSPTO_2964 | PSPTO_4179 | Conserved hypothetical protein; Similar to GP:17431911; identified by sequence similarity; putative; Belongs to the class-I aminoacyl-tRNA synthetase family. | 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 0.903 |
AAO56456.1 | metG | PSPTO_2964 | PSPTO_4147 | Conserved hypothetical protein; Similar to GP:17431911; identified by sequence similarity; putative; Belongs to the class-I aminoacyl-tRNA synthetase family. | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.947 |
AAO56456.1 | metH | PSPTO_2964 | PSPTO_2732 | Conserved hypothetical protein; Similar to GP:17431911; identified by sequence similarity; putative; Belongs to the class-I aminoacyl-tRNA synthetase family. | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.914 |
AAO56456.1 | pheT | PSPTO_2964 | PSPTO_2383 | Conserved hypothetical protein; Similar to GP:17431911; identified by sequence similarity; putative; Belongs to the class-I aminoacyl-tRNA synthetase family. | phenylalanyl-tRNA synthetase, beta subunit; See PMID:20190049 for expression data; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.804 |
AAO56456.1 | purL | PSPTO_2964 | PSPTO_1459 | Conserved hypothetical protein; Similar to GP:17431911; identified by sequence similarity; putative; Belongs to the class-I aminoacyl-tRNA synthetase family. | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.458 |
fdxA | metG | PSPTO_4059 | PSPTO_4147 | Ferredoxin; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.906 |
fmt | AAO56456.1 | PSPTO_0178 | PSPTO_2964 | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | Conserved hypothetical protein; Similar to GP:17431911; identified by sequence similarity; putative; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.919 |
fmt | ileS | PSPTO_0178 | PSPTO_0806 | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. | 0.464 |
fmt | leuS | PSPTO_0178 | PSPTO_4812 | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | leucyl-tRNA synthetase; See PMID:20190049 for expression data; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.570 |
fmt | metG | PSPTO_0178 | PSPTO_4147 | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.941 |
fmt | metH | PSPTO_0178 | PSPTO_2732 | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.948 |
fmt | pheS | PSPTO_0178 | PSPTO_2382 | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | phenylalanyl-tRNA synthetase, alpha subunit; See PMID:20190049 for expression data; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. | 0.575 |
fmt | pheT | PSPTO_0178 | PSPTO_2383 | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | phenylalanyl-tRNA synthetase, beta subunit; See PMID:20190049 for expression data; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.681 |
fmt | purL | PSPTO_0178 | PSPTO_1459 | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.439 |
ileS | AAO56456.1 | PSPTO_0806 | PSPTO_2964 | isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. | Conserved hypothetical protein; Similar to GP:17431911; identified by sequence similarity; putative; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.778 |
ileS | fmt | PSPTO_0806 | PSPTO_0178 | isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | 0.464 |
ileS | leuS | PSPTO_0806 | PSPTO_4812 | isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. | leucyl-tRNA synthetase; See PMID:20190049 for expression data; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.915 |