STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
phhAPhenylalanine-4-hydroxylase; Identified by match to TIGR protein family HMM TIGR01270. (265 aa)    
Predicted Functional Partners:
phhB
Pterin-4-alpha-carbinolamine dehydratase; Involved in tetrahydrobiopterin biosynthesis. Seems to both prevent the formation of 7-pterins and accelerate the formation of quinonoid-BH2. May also have a positive regulatory role in the expression of phhA (By similarity); Belongs to the pterin-4-alpha-carbinolamine dehydratase family.
 
 0.995
aspC
Aspartate aminotransferase; See PMID:20190049 for expression data.
  
 
 0.942
tyrB
Aromatic-amino-acid aminotransferase; See PMID:20190049 for expression data; similar to GP:13364513, and SP:P04693; identified by sequence similarity; putative.
  
 
 0.942
pheA
Chorismate mutase/prephenate dehydratase; See PMID:20190049 for expression data.
    
 0.937
AAO55268.1
Prephenate dehydrogenase/3-phosphoshikimate 1-carboxyvinyltransferase family protein; See PMID:20190049 for expression data.
    
 0.918
hisC
Histidinol-phosphate aminotransferase; Identified by match to TIGR protein family HMM TIGR01265; see PMID:20190049 for expression data; identified by match to TIGR protein family HMM TIGR01265; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
     
 0.911
hppD
4-hydroxyphenylpyruvate dioxygenase; Identified by match to PFAM protein family HMM PF00903; see PMID:20190049 for expression data; identified by match to PFAM protein family HMM PF00903.
 
  
 0.908
aspB
Aspartate aminotransferase; Similar to SP:P53001; identified by sequence similarity; putative.
   
 
 0.906
folA
Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
     
 0.902
AAO54857.1
Cyclohexadienyl dehydratase, putative; See PMID:20190049 for expression data; similar to SP:Q01269, GB:M34462, GB:M35670, GB:M36805, GB:X65787, GB:Y00809, GB:Z26248, SP:P13727, PID:182080, PID:187415, PID:306839, PID:31137, PID:312045, PID:34476, and PID:400414; identified by sequence similarity; putative.
     
  0.900
Your Current Organism:
Pseudomonas syringae tomato
NCBI taxonomy Id: 223283
Other names: P. syringae pv. tomato str. DC3000, Pseudomonas syringae DC3000, Pseudomonas syringae pv. tomato DC3000, Pseudomonas syringae pv. tomato str. ATCC BAA-871, Pseudomonas syringae pv. tomato str. DC3000
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