Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
phhBPterin-4-alpha-carbinolamine dehydratase; Involved in tetrahydrobiopterin biosynthesis. Seems to both prevent the formation of 7-pterins and accelerate the formation of quinonoid-BH2. May also have a positive regulatory role in the expression of phhA (By similarity); Belongs to the pterin-4-alpha-carbinolamine dehydratase family. (118 aa)    
Predicted Functional Partners:
phhA
Phenylalanine-4-hydroxylase; Identified by match to TIGR protein family HMM TIGR01270.
 
 0.999
hmgA
Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.
  
  
 0.791
hppD
4-hydroxyphenylpyruvate dioxygenase; Identified by match to PFAM protein family HMM PF00903; see PMID:20190049 for expression data; identified by match to PFAM protein family HMM PF00903.
  
  
 0.782
AAO54710.1
Oxidoreductase, short chain dehydrogenase/reductase family; See PMID:20190049 for expression data; similar to GB:X68505, GB:X68505, GB:X63381, GB:X63381, SP:Q02078, SP:Q02080, PID:1197538, PID:34536, and PID:432656; identified by sequence similarity; putative.
   
  
 0.647
aspC
Aspartate aminotransferase; See PMID:20190049 for expression data.
  
  
 0.547
tyrB
Aromatic-amino-acid aminotransferase; See PMID:20190049 for expression data; similar to GP:13364513, and SP:P04693; identified by sequence similarity; putative.
  
  
 0.547
fahA
Fumarylacetoacetase; See PMID:20190049 for expression data.
  
  
 0.535
maiA
Maleylacetoacetate isomerase; See PMID:20190049 for expression data; identified by match to PFAM protein family HMM PF02798.
  
  
 0.521
AAO57790.1
Fumarate hydratase, class I, putative; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
     
 0.497
pheA
Chorismate mutase/prephenate dehydratase; See PMID:20190049 for expression data.
      
 0.479
Your Current Organism:
Pseudomonas syringae tomato
NCBI taxonomy Id: 223283
Other names: P. syringae pv. tomato str. DC3000, Pseudomonas syringae DC3000, Pseudomonas syringae pv. tomato DC3000, Pseudomonas syringae pv. tomato str. ATCC BAA-871, Pseudomonas syringae pv. tomato str. DC3000
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