node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AAO58469.1 | carA | PSPTO_5041 | PSPTO_4502 | Dihydroorotase, multifunctional complex type; See PMID:20190049 for expression data. | Carbamoyl-phosphate synthase, small subunit; See PMID:20190049 for expression data; Belongs to the CarA family. | 0.994 |
AAO58469.1 | carB | PSPTO_5041 | PSPTO_4501 | Dihydroorotase, multifunctional complex type; See PMID:20190049 for expression data. | Carbamoyl-phosphate synthase, large subunit; See PMID:20190049 for expression data. | 0.995 |
AAO58469.1 | purA | PSPTO_5041 | PSPTO_4937 | Dihydroorotase, multifunctional complex type; See PMID:20190049 for expression data. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.417 |
AAO58469.1 | pyrB | PSPTO_5041 | PSPTO_5040 | Dihydroorotase, multifunctional complex type; See PMID:20190049 for expression data. | Aspartate carbamoyltransferase; See PMID:20190049 for expression data; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.999 |
AAO58469.1 | pyrC | PSPTO_5041 | PSPTO_4157 | Dihydroorotase, multifunctional complex type; See PMID:20190049 for expression data. | Dihydroorotase, homodimeric type; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate. | 0.919 |
AAO58469.1 | pyrD | PSPTO_5041 | PSPTO_2309 | Dihydroorotase, multifunctional complex type; See PMID:20190049 for expression data. | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | 0.994 |
AAO58469.1 | pyrE | PSPTO_5041 | PSPTO_0080 | Dihydroorotase, multifunctional complex type; See PMID:20190049 for expression data. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.940 |
AAO58469.1 | pyrF | PSPTO_5041 | PSPTO_2028 | Dihydroorotase, multifunctional complex type; See PMID:20190049 for expression data. | Orotidine 5-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.948 |
AAO58469.1 | pyrR | PSPTO_5041 | PSPTO_5039 | Dihydroorotase, multifunctional complex type; See PMID:20190049 for expression data. | Pyrimidine operon regulatory protein PyrR; Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines. | 0.996 |
asnB | carB | PSPTO_1633 | PSPTO_4501 | Asparagine synthetase, glutamine-hydrolyzing. | Carbamoyl-phosphate synthase, large subunit; See PMID:20190049 for expression data. | 0.433 |
asnB | purA | PSPTO_1633 | PSPTO_4937 | Asparagine synthetase, glutamine-hydrolyzing. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.939 |
asnB | pyrB | PSPTO_1633 | PSPTO_5040 | Asparagine synthetase, glutamine-hydrolyzing. | Aspartate carbamoyltransferase; See PMID:20190049 for expression data; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.928 |
carA | AAO58469.1 | PSPTO_4502 | PSPTO_5041 | Carbamoyl-phosphate synthase, small subunit; See PMID:20190049 for expression data; Belongs to the CarA family. | Dihydroorotase, multifunctional complex type; See PMID:20190049 for expression data. | 0.994 |
carA | carB | PSPTO_4502 | PSPTO_4501 | Carbamoyl-phosphate synthase, small subunit; See PMID:20190049 for expression data; Belongs to the CarA family. | Carbamoyl-phosphate synthase, large subunit; See PMID:20190049 for expression data. | 0.999 |
carA | purA | PSPTO_4502 | PSPTO_4937 | Carbamoyl-phosphate synthase, small subunit; See PMID:20190049 for expression data; Belongs to the CarA family. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.682 |
carA | pyrB | PSPTO_4502 | PSPTO_5040 | Carbamoyl-phosphate synthase, small subunit; See PMID:20190049 for expression data; Belongs to the CarA family. | Aspartate carbamoyltransferase; See PMID:20190049 for expression data; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.999 |
carA | pyrC | PSPTO_4502 | PSPTO_4157 | Carbamoyl-phosphate synthase, small subunit; See PMID:20190049 for expression data; Belongs to the CarA family. | Dihydroorotase, homodimeric type; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate. | 0.550 |
carA | pyrD | PSPTO_4502 | PSPTO_2309 | Carbamoyl-phosphate synthase, small subunit; See PMID:20190049 for expression data; Belongs to the CarA family. | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | 0.960 |
carA | pyrE | PSPTO_4502 | PSPTO_0080 | Carbamoyl-phosphate synthase, small subunit; See PMID:20190049 for expression data; Belongs to the CarA family. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.925 |
carA | pyrF | PSPTO_4502 | PSPTO_2028 | Carbamoyl-phosphate synthase, small subunit; See PMID:20190049 for expression data; Belongs to the CarA family. | Orotidine 5-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.926 |