STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rimOConserved hypothetical protein TIGR01125; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily. (443 aa)    
Predicted Functional Partners:
AAO57479.1
Conserved protein of unknown function; See PMID:20190049 for expression data; similar to GP:15979249; identified by sequence similarity; putative.
  
    0.609
AAO57477.1
Acetyltransferase, GNAT family; Similar to GB:M23419, GB:U17969, SP:P10159, PID:181997, and PID:602245; identified by sequence similarity; putative.
  
    0.594
AAO57475.1
Conserved hypothetical protein; Similar to SP:P77698, SP:Q01624, and PID:46680; identified by sequence similarity; putative.
       0.582
thiI
Thiamin biosynthesis protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
  
  
 0.569
lepB
Signal peptidase I; See PMID:20190049 for expression data; similar to SP:P26844; identified by sequence similarity; putative; Belongs to the peptidase S26 family.
  
    0.549
rlmN
Radical SAM enzyme, Cfr family; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family.
 
  
 0.526
glnS
glutaminyl-tRNA synthetase; Identified by match to TIGR protein family HMM TIGR00464; see PMID:20190049 for expression data; identified by match to TIGR protein family HMM TIGR00464.
   
  
 0.453
AAO57478.1
S4 domain protein; See PMID:20190049 for expression data; identified by match to PFAM protein family HMM PF01479.
  
    0.451
prfA
Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
  
  
 0.448
parC
DNA topoisomerase IV, A subunit; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
   
  
 0.442
Your Current Organism:
Pseudomonas syringae tomato
NCBI taxonomy Id: 223283
Other names: P. syringae pv. tomato str. DC3000, Pseudomonas syringae DC3000, Pseudomonas syringae pv. tomato DC3000, Pseudomonas syringae pv. tomato str. ATCC BAA-871, Pseudomonas syringae pv. tomato str. DC3000
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