STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sdhASuccinate dehydrogenase, flavoprotein subunit; Similar to SP:P10444, GB:D12485, GB:M57736, SP:P22413, PID:189650, PID:219944, and PID:219945; identified by sequence similarity; putative; see PMID:20190049 for expression data; similar to SP:P10444, GB:D12485, GB:M57736, SP:P22413, PID:189650, PID:219944, and PID:219945, identified by sequence similarity, putative; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (590 aa)    
Predicted Functional Partners:
sdhC
Succinate dehydrogenase, cytochrome b556 subunit; See PMID:20190049 for expression data; similar to GP:9947544, and SP:P10446; identified by sequence similarity; putative.
 
 0.999
sdhB
Succinate dehydrogenase, iron-sulfur protein; Similar to SP:P07014, GB:L05004, and PID:152957; identified by sequence similarity; putative; see PMID:20190049 for expression data; similar to SP:P07014, GB:L05004, and PID:152957, identified by sequence similarity, putative.
 
 0.999
AAO55712.1
Succinate dehydrogenase, hydrophobic membrane anchor protein; Membrane-anchoring subunit of succinate dehydrogenase (SDH).
 
 0.998
AAO57790.1
Fumarate hydratase, class I, putative; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
  
 
 0.997
sucD
succinyl-CoA synthase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
 
 0.993
sucC
succinyl-CoA synthase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
 
 0.991
fumC-1
Fumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
 
 0.985
fumC-2
Fumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
 0.981
nuoCD
NADH dehydrogenase I, C/D subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the N-terminal section; belongs to the complex I 30 kDa subunit family.
  
 
 0.971
sucA
2-oxoglutarate dehydrogenase, E1 component; Identified by match to PFAM protein family HMM PF02779; see PMID:20190049 for expression data; identified by match to PFAM protein family HMM PF02779.
  
 
 0.946
Your Current Organism:
Pseudomonas syringae tomato
NCBI taxonomy Id: 223283
Other names: P. syringae pv. tomato str. DC3000, Pseudomonas syringae DC3000, Pseudomonas syringae pv. tomato DC3000, Pseudomonas syringae pv. tomato str. ATCC BAA-871, Pseudomonas syringae pv. tomato str. DC3000
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.