Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
tpxThiol peroxidase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Tpx subfamily. (166 aa)    
Predicted Functional Partners:
sodB
Superoxide dismutase, Fe; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
  
  
 0.820
sodA
Superoxide dismutase, Mn; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
  
  
 0.816
AAO55301.1
Glutathione peroxidase family protein; See PMID:20190049 for expression data; Belongs to the glutathione peroxidase family.
   
  
 0.792
AAO54699.1
Glutathione peroxidase family protein; See PMID:20190049 for expression data; Belongs to the glutathione peroxidase family.
   
  
 0.791
AAO55239.1
Glutathione peroxidase family protein; See PMID:20190049 for expression data; Belongs to the glutathione peroxidase family.
   
  
 0.791
ahpC
Alkyl hydroperoxide reductase, subunit C; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
  
  
 0.779
katG
Catalase/peroxidase HPI; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity; Belongs to the peroxidase family. Peroxidase/catalase subfamily.
      
 0.760
AAO56254.1
HlyD family secretion protein; See PMID:20190049 for expression data; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
       0.755
AAO56250.1
Conserved hypothetical protein; Identified by match to PFAM protein family HMM PF01103.
       0.694
AAO56251.1
Conserved hypothetical protein; Similar to GP:9948600; identified by sequence similarity; putative.
       0.694
Your Current Organism:
Pseudomonas syringae tomato
NCBI taxonomy Id: 223283
Other names: P. syringae pv. tomato str. DC3000, Pseudomonas syringae DC3000, Pseudomonas syringae pv. tomato DC3000, Pseudomonas syringae pv. tomato str. ATCC BAA-871, Pseudomonas syringae pv. tomato str. DC3000
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