STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CCDC57Coiled-coil domain containing 57. (821 aa)    
Predicted Functional Partners:
PLK4
Polo like kinase 4.
    
 0.574
PLK3
Polo like kinase 3.
    
 0.574
PLK1
Polo like kinase 1.
    
 0.574
PLK2
Polo like kinase 2.
    
 0.574
PPP2R2A
Protein phosphatase 2 regulatory subunit Balpha.
    
 0.551
PPP2R2B
Protein phosphatase 2 regulatory subunit Bbeta.
    
 0.551
EGFR
Epidermal growth factor receptor.
    
 0.548
ERBB2
Erb-b2 receptor tyrosine kinase 2.
    
 0.548
ERBB3
Erb-b2 receptor tyrosine kinase 3.
    
 0.548
ERBB4
Erb-b2 receptor tyrosine kinase 4.
    
 0.548
Your Current Organism:
Aquila chrysaetos
NCBI taxonomy Id: 223781
Other names: A. chrysaetos chrysaetos, Aquila chrysaetos chrysaetos
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.