STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMOSmoothened, frizzled class receptor. (802 aa)    
Predicted Functional Partners:
PTCH2
Patched 2.
    
 0.980
PTCH1
Patched 1.
    
 0.980
KIF7
Kinesin family member 7.
   
 0.974
KIF21B
Kinesin family member 21B.
   
 0.971
PRKACB
Protein kinase cAMP-activated catalytic subunit beta.
    
 0.936
GKAP1
G kinase anchoring protein 1.
   
 0.935
SUFU
SUFU negative regulator of hedgehog signaling.
     
 0.924
PRKX
Protein kinase X-linked.
    
 0.917
EVC
EvC ciliary complex subunit 1.
     
 0.902
EVC2
EvC ciliary complex subunit 2.
     
 0.902
Your Current Organism:
Aquila chrysaetos
NCBI taxonomy Id: 223781
Other names: A. chrysaetos chrysaetos, Aquila chrysaetos chrysaetos
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.