STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ESCO1Establishment of sister chromatid cohesion N-acetyltransferase 1. (847 aa)    
Predicted Functional Partners:
SMC3
Structural maintenance of chromosomes 3.
   
 0.982
PDS5A
PDS5 cohesin associated factor A.
    
 0.929
SMC1B
Structural maintenance of chromosomes 1B.
   
 0.914
PDS5B
PDS5 cohesin associated factor B.
   
 0.895
SMC4
Structural maintenance of chromosomes 4.
   
 0.889
SMC2
Structural maintenance of chromosomes 2.
   
 0.888
RAD21
RAD21 cohesin complex component.
   
 0.881
ENSACCP00020010430
annotation not available
   
 0.881
SMC5
Structural maintenance of chromosomes 5.
   
 0.880
PCNA
Proliferating cell nuclear antigen.
   
 0.867
Your Current Organism:
Aquila chrysaetos
NCBI taxonomy Id: 223781
Other names: A. chrysaetos chrysaetos, Aquila chrysaetos chrysaetos
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.