STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C12orf4Chromosome 17 C12orf4 homolog. (550 aa)    
Predicted Functional Partners:
PPP1R21
Protein phosphatase 1 regulatory subunit 21.
    
 
 0.727
TBCK
TBC1 domain containing kinase.
    
 
 0.713
EXOC8
Exocyst complex component 8.
   
    0.699
TBC1D31
TBC1 domain family member 31.
    
 
 0.544
IL6R
Interleukin 6 receptor.
    
   0.489
ZNF330
Zinc finger protein 330.
      
 0.480
TMEM106C
Transmembrane protein 106C.
      
 0.461
CRYZL1
Crystallin zeta like 1.
   
   0.426
Your Current Organism:
Aquila chrysaetos
NCBI taxonomy Id: 223781
Other names: A. chrysaetos chrysaetos, Aquila chrysaetos chrysaetos
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.