STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MAP3K5Mitogen-activated protein kinase kinase kinase 5. (1356 aa)    
Predicted Functional Partners:
MAP2K4
Mitogen-activated protein kinase kinase 4.
   
0.936
TXN
Thioredoxin.
    
 0.903
TRAF2
TNF receptor associated factor 2.
    
 0.900
TRAF4
TNF receptor associated factor 4.
    
 0.872
PARK7
Parkinsonism associated deglycase.
    
 0.871
DAB2IP
DAB2 interacting protein.
    
 0.855
MAP2K6
Mitogen-activated protein kinase kinase 6.
   
0.847
MAP2K3
Mitogen-activated protein kinase kinase 3.
   
0.847
TRAF1
TNF receptor associated factor 1.
    
 0.846
MAP2K7
Mitogen-activated protein kinase kinase 7.
    
0.844
Your Current Organism:
Aquila chrysaetos
NCBI taxonomy Id: 223781
Other names: A. chrysaetos chrysaetos, Aquila chrysaetos chrysaetos
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.