STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SESN2Sestrin 2. (474 aa)    
Predicted Functional Partners:
DEPDC5
DEP domain containing 5, GATOR1 subcomplex subunit.
    
 0.987
WDR24
WD repeat domain 24.
    
 0.964
ULK1
Unc-51 like autophagy activating kinase 1.
    
 0.962
MIOS
Meiosis regulator for oocyte development.
    
 0.956
RICTOR
RPTOR independent companion of MTOR complex 2.
     
 0.944
ATG13
Autophagy related 13.
    
 0.938
MTOR
Mechanistic target of rapamycin kinase.
     
 0.938
RB1CC1
RB1 inducible coiled-coil 1.
    
 0.937
PRKAA2
Protein kinase AMP-activated catalytic subunit alpha 2.
     
 0.936
RPTOR
Regulatory associated protein of MTOR complex 1.
     
 0.929
Your Current Organism:
Aquila chrysaetos
NCBI taxonomy Id: 223781
Other names: A. chrysaetos chrysaetos, Aquila chrysaetos chrysaetos
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.