STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ERCC4ERCC excision repair 4, endonuclease catalytic subunit. (903 aa)    
Predicted Functional Partners:
ERCC1
ERCC excision repair 1, endonuclease non-catalytic subunit.
   
 0.999
XPA
XPA, DNA damage recognition and repair factor.
    
 0.997
SLX4
SLX4 structure-specific endonuclease subunit.
  
 0.996
MSH2
mutS homolog 2.
    
 0.988
TOP3A
DNA topoisomerase III alpha.
    
 0.983
ERCC3
ERCC excision repair 3, TFIIH core complex helicase subunit.
  
 0.977
TP53BP1
Tumor protein p53 binding protein 1.
    
 0.976
NARS1
asparaginyl-tRNA synthetase 1.
  
 0.976
MSH3
mutS homolog 3.
    
 0.974
XPC
XPC complex subunit, DNA damage recognition and repair factor.
    
 0.973
Your Current Organism:
Aquila chrysaetos
NCBI taxonomy Id: 223781
Other names: A. chrysaetos chrysaetos, Aquila chrysaetos chrysaetos
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.