STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
JAK2Janus kinase 2. (1130 aa)    
Predicted Functional Partners:
STAT3
Signal transducer and activator of transcription 3.
   
 0.991
SOCS3
Suppressor of cytokine signaling 3.
   
 0.989
SOCS1
Suppressor of cytokine signaling 1.
   
 0.982
LEPR
Leptin receptor.
    
 0.979
CSF2RB
Colony stimulating factor 2 receptor beta common subunit.
   
 0.970
GHR
Growth hormone receptor.
    
 0.963
IL6ST
Interleukin 6 signal transducer.
    
 0.943
CSF3R
Colony stimulating factor 3 receptor.
   
 0.942
IL10RA
Interleukin 10 receptor subunit alpha.
   
 0.941
IFNGR2
Interferon gamma receptor 2.
   
 0.941
Your Current Organism:
Aquila chrysaetos
NCBI taxonomy Id: 223781
Other names: A. chrysaetos chrysaetos, Aquila chrysaetos chrysaetos
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.