STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ERBB3Erb-b2 receptor tyrosine kinase 3. (1145 aa)    
Predicted Functional Partners:
MST1R
Macrophage stimulating 1 receptor.
   
0.943
MET
MET proto-oncogene, receptor tyrosine kinase.
   
0.943
GRB2
Growth factor receptor bound protein 2.
    
 0.937
CBLB
Cbl proto-oncogene B.
    
 0.906
CBL
Cbl proto-oncogene.
    
 0.906
EGF
Epidermal growth factor.
   
 0.904
SOS1
SOS Ras/Rac guanine nucleotide exchange factor 1.
    
 0.891
SHC1
SHC adaptor protein 1.
    
 0.887
NRG2
Neuregulin 2.
    
 0.885
NRG1
Neuregulin 1.
    
 0.885
Your Current Organism:
Aquila chrysaetos
NCBI taxonomy Id: 223781
Other names: A. chrysaetos chrysaetos, Aquila chrysaetos chrysaetos
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.