STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PRLRProlactin receptor. (831 aa)    
Predicted Functional Partners:
PRL
Prolactin.
    
 0.993
ENSACCP00020023027
annotation not available
    
 0.986
ENSACCP00020023410
annotation not available
   
 0.957
JAK2
Janus kinase 2.
    
 0.928
IFNAR1
Interferon alpha and beta receptor subunit 1.
  
  
 0.880
CISH
Cytokine inducible SH2 containing protein.
    
 0.872
TYK2
Tyrosine kinase 2.
    
 0.860
JAK1
Janus kinase 1.
    
 0.860
IL15
Interleukin 15.
  
  
  0.856
TFRC
Transferrin receptor.
     
 0.854
Your Current Organism:
Aquila chrysaetos
NCBI taxonomy Id: 223781
Other names: A. chrysaetos chrysaetos, Aquila chrysaetos chrysaetos
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.