STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFP64941.1cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases. (225 aa)    
Predicted Functional Partners:
SFP28160.1
Adenylate cyclase.
 
 
 0.979
rpoC
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.955
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
   0.908
SFP51009.1
PAS domain S-box-containing protein.
   
 0.887
SFP32945.1
Response regulator receiver domain-containing protein.
   
 0.884
SFP53064.1
6-pyruvoyltetrahydropterin/6- carboxytetrahydropterin synthase.
    
  0.880
rpoZ
DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
    
 
 0.871
SFP03076.1
ABC-type nitrate/sulfonate/bicarbonate transport system, substrate-binding protein.
   
 0.868
SFP03142.1
Polar amino acid transport system substrate-binding protein.
   
 0.868
SFO92487.1
CRP/FNR family transcriptional regulator, anaerobic regulatory protein.
  
  
  0.867
Your Current Organism:
Hydrogenimonas thermophila
NCBI taxonomy Id: 223786
Other names: ATCC BAA-737, H. thermophila, Hydrogenimonas thermophila Takai et al. 2004, JCM 11971, strain EP1-55-1%
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