STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC108743175N-acylneuraminate-9-phosphatase isoform X1. (254 aa)    
Predicted Functional Partners:
LOC108734760
Influenza virus NS1A-binding protein.
   
 
 0.942
LOC108735300
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
  
 0.925
LOC108732819
Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
  
 
 0.904
LOC108743255
S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
  
 
 0.899
LOC108735925
Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.
    
 0.892
LOC108732756
Coronin; Belongs to the WD repeat coronin family.
    
 0.890
LOC108741688
Coronin; Belongs to the WD repeat coronin family.
    
 0.890
LOC108739319
CDP-diacylglycerol--inositol 3-phosphatidyltransferase.
  
 
 0.882
LOC108737246
Phosphomannomutase; Involved in the synthesis of the GDP-mannose and dolichol- phosphate-mannose required for a number of critical mannosyl transfer reactions.
    
 0.876
LOC108742898
Riboflavin kinase.
  
 
 0.870
Your Current Organism:
Agrilus planipennis
NCBI taxonomy Id: 224129
Other names: A. planipennis, Agrilus feretrius, Agrilus marcopoli, emerald ash borer
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