node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
drm | guaA | BSU23500 | BSU06360 | Phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose | Gmp synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP | 0.699 |
drm | pdxS | BSU23500 | BSU00110 | Phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose | Glutamine amidotransferase for pyridoxal phosphate synthesis; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively | 0.800 |
drm | pdxT | BSU23500 | BSU00120 | Phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose | Glutamine amidotransferase for pyridoxal phosphate synthesis; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS | 0.800 |
drm | pgcA | BSU23500 | BSU09310 | Phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose | Alpha-phosphoglucomutase; Catalyzes the interconversion between glucose-6-phosphate and alpha-glucose-1-phosphate. This is the first step in the biosynthesis of diglucosyl-diacylglycerol (Glc2-DAG), i.e. the predominant glycolipid found in B.subtilis membrane, which is also used as a membrane anchor for lipoteichoic acid (LTA). Has a role in the biosynthesis of all phosphate-containing envelope polymers, since glucose-1-phosphate is the precursor of UDP-glucose, which serves as a glucosyl donor not only for the biosynthesis of LTA but also for wall teichoic acids (WTAs). Is required fo [...] | 0.910 |
drm | prs | BSU23500 | BSU00510 | Phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose | Phosphoribosylpyrophosphate synthetase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P) | 0.955 |
drm | rbsK | BSU23500 | BSU35920 | Phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose | Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway | 0.902 |
drm | tkt | BSU23500 | BSU17890 | Phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate | 0.905 |
drm | ywlF | BSU23500 | BSU36920 | Phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose | Ribose 5-phosphate isomerase b; Putative sugar phosphate isomerase YwlF; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme | 0.918 |
guaA | drm | BSU06360 | BSU23500 | Gmp synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP | Phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose | 0.699 |
guaA | pdxK | BSU06360 | BSU38020 | Gmp synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP | Phosphorylates B6 vitamers; functions in a salvage pathway. Uses pyridoxal, pyridoxine, and pyridoxamine as substrates. Can also use hydroxymethylpyrimidine (HMP) as substrate | 0.726 |
guaA | pdxS | BSU06360 | BSU00110 | Gmp synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP | Glutamine amidotransferase for pyridoxal phosphate synthesis; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively | 0.799 |
guaA | pdxT | BSU06360 | BSU00120 | Gmp synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP | Glutamine amidotransferase for pyridoxal phosphate synthesis; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS | 0.924 |
guaA | prs | BSU06360 | BSU00510 | Gmp synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP | Phosphoribosylpyrophosphate synthetase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P) | 0.954 |
guaA | tkt | BSU06360 | BSU17890 | Gmp synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate | 0.635 |
guaA | ywlF | BSU06360 | BSU36920 | Gmp synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP | Ribose 5-phosphate isomerase b; Putative sugar phosphate isomerase YwlF; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme | 0.433 |
pdxK | guaA | BSU38020 | BSU06360 | Phosphorylates B6 vitamers; functions in a salvage pathway. Uses pyridoxal, pyridoxine, and pyridoxamine as substrates. Can also use hydroxymethylpyrimidine (HMP) as substrate | Gmp synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP | 0.726 |
pdxK | pdxS | BSU38020 | BSU00110 | Phosphorylates B6 vitamers; functions in a salvage pathway. Uses pyridoxal, pyridoxine, and pyridoxamine as substrates. Can also use hydroxymethylpyrimidine (HMP) as substrate | Glutamine amidotransferase for pyridoxal phosphate synthesis; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively | 0.954 |
pdxK | pdxT | BSU38020 | BSU00120 | Phosphorylates B6 vitamers; functions in a salvage pathway. Uses pyridoxal, pyridoxine, and pyridoxamine as substrates. Can also use hydroxymethylpyrimidine (HMP) as substrate | Glutamine amidotransferase for pyridoxal phosphate synthesis; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS | 0.973 |
pdxK | rbsK | BSU38020 | BSU35920 | Phosphorylates B6 vitamers; functions in a salvage pathway. Uses pyridoxal, pyridoxine, and pyridoxamine as substrates. Can also use hydroxymethylpyrimidine (HMP) as substrate | Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway | 0.415 |
pdxK | tkt | BSU38020 | BSU17890 | Phosphorylates B6 vitamers; functions in a salvage pathway. Uses pyridoxal, pyridoxine, and pyridoxamine as substrates. Can also use hydroxymethylpyrimidine (HMP) as substrate | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate | 0.493 |