| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| dnaX | pcrA | BSU00190 | BSU06610 | DNA polymerase III (gamma and tau subunits); DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. | ATP-dependent DNA helicase; DNA helicase used for plasmid rolling-circle replication and also involved in UV repair. | 0.514 |
| dnaX | recA | BSU00190 | BSU16940 | DNA polymerase III (gamma and tau subunits); DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. | Multifunctional SOS repair factor; Multifunctional protein involved in homologous recombination, DNA repair and competence. Can catalyze the hydrolysis of (d)ATP in the presence of single-stranded DNA; prefers dATP at least in vitro, catalyzes the dATP-dependent uptake of single- stranded DNA by duplex DNA, and the dATP-dependent hybridization of homologous single-stranded DNAs (strand exchange). RecA-ATP cannot catalyze homologous DNA strand exchange; SsbA and DprA activate strand exchange by RecA-ATP. It interacts with LexA causing its activation and leading to its autocatalytic clea [...] | 0.820 |
| dnaX | recF | BSU00190 | BSU00040 | DNA polymerase III (gamma and tau subunits); DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. | DNA repair and genetic recombination factor; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. Is recruited to repair centers, foci that are the site of double- strand DNA break(s) after RecN and RecO; recruitment may depend on RecO. | 0.678 |
| dnaX | recG | BSU00190 | BSU15870 | DNA polymerase III (gamma and tau subunits); DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. | Branch migrating ATP-dependent DNA helicase involved in DNA recombination and repair; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA) (By similarity); Belongs to the helicase family. RecG subfamily. | 0.642 |
| dnaX | recJ | BSU00190 | BSU27620 | DNA polymerase III (gamma and tau subunits); DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. | Putative single-strand DNA-specific exonuclease; Putative single-stranded-DNA-specific exonuclease (By similarity). RecA thread formation during DNA double-strand break repair requires RecJ or AadAB; Belongs to the RecJ family. | 0.558 |
| dnaX | recN | BSU00190 | BSU24240 | DNA polymerase III (gamma and tau subunits); DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. | Factor for double strand breaks DNA repair and genetic recombination; Involved in recombinational repair of damaged DNA. Seems to be the first protein recruited to repair centers, foci that are the site of double-strand DNA break(s), followed by RecO and then RecF. | 0.680 |
| dnaX | recO | BSU00190 | BSU25280 | DNA polymerase III (gamma and tau subunits); DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. | DNA double strand break repair and homologous recombination factor; Plays a role in DNA double-stranded break repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecR. Is recruited to repair centers, foci that are the site of double-strand break(s) after RecN and before RecF; may actively recruit RecF. | 0.812 |
| dnaX | recR | BSU00190 | BSU00210 | DNA polymerase III (gamma and tau subunits); DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. | DNA repair and recombination protein; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. | 0.981 |
| dnaX | recX | BSU00190 | BSU08520 | DNA polymerase III (gamma and tau subunits); DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. | Regulatory protein RecX; Modulates RecA activity; Belongs to the RecX family. | 0.573 |
| dnaX | yaaK | BSU00190 | BSU00200 | DNA polymerase III (gamma and tau subunits); DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. | DNA binding protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection. | 0.926 |
| pcrA | dnaX | BSU06610 | BSU00190 | ATP-dependent DNA helicase; DNA helicase used for plasmid rolling-circle replication and also involved in UV repair. | DNA polymerase III (gamma and tau subunits); DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. | 0.514 |
| pcrA | recA | BSU06610 | BSU16940 | ATP-dependent DNA helicase; DNA helicase used for plasmid rolling-circle replication and also involved in UV repair. | Multifunctional SOS repair factor; Multifunctional protein involved in homologous recombination, DNA repair and competence. Can catalyze the hydrolysis of (d)ATP in the presence of single-stranded DNA; prefers dATP at least in vitro, catalyzes the dATP-dependent uptake of single- stranded DNA by duplex DNA, and the dATP-dependent hybridization of homologous single-stranded DNAs (strand exchange). RecA-ATP cannot catalyze homologous DNA strand exchange; SsbA and DprA activate strand exchange by RecA-ATP. It interacts with LexA causing its activation and leading to its autocatalytic clea [...] | 0.988 |
| pcrA | recF | BSU06610 | BSU00040 | ATP-dependent DNA helicase; DNA helicase used for plasmid rolling-circle replication and also involved in UV repair. | DNA repair and genetic recombination factor; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. Is recruited to repair centers, foci that are the site of double- strand DNA break(s) after RecN and RecO; recruitment may depend on RecO. | 0.880 |
| pcrA | recG | BSU06610 | BSU15870 | ATP-dependent DNA helicase; DNA helicase used for plasmid rolling-circle replication and also involved in UV repair. | Branch migrating ATP-dependent DNA helicase involved in DNA recombination and repair; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA) (By similarity); Belongs to the helicase family. RecG subfamily. | 0.923 |
| pcrA | recJ | BSU06610 | BSU27620 | ATP-dependent DNA helicase; DNA helicase used for plasmid rolling-circle replication and also involved in UV repair. | Putative single-strand DNA-specific exonuclease; Putative single-stranded-DNA-specific exonuclease (By similarity). RecA thread formation during DNA double-strand break repair requires RecJ or AadAB; Belongs to the RecJ family. | 0.802 |
| pcrA | recN | BSU06610 | BSU24240 | ATP-dependent DNA helicase; DNA helicase used for plasmid rolling-circle replication and also involved in UV repair. | Factor for double strand breaks DNA repair and genetic recombination; Involved in recombinational repair of damaged DNA. Seems to be the first protein recruited to repair centers, foci that are the site of double-strand DNA break(s), followed by RecO and then RecF. | 0.517 |
| pcrA | recO | BSU06610 | BSU25280 | ATP-dependent DNA helicase; DNA helicase used for plasmid rolling-circle replication and also involved in UV repair. | DNA double strand break repair and homologous recombination factor; Plays a role in DNA double-stranded break repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecR. Is recruited to repair centers, foci that are the site of double-strand break(s) after RecN and before RecF; may actively recruit RecF. | 0.886 |
| pcrA | recR | BSU06610 | BSU00210 | ATP-dependent DNA helicase; DNA helicase used for plasmid rolling-circle replication and also involved in UV repair. | DNA repair and recombination protein; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. | 0.938 |
| pcrA | recX | BSU06610 | BSU08520 | ATP-dependent DNA helicase; DNA helicase used for plasmid rolling-circle replication and also involved in UV repair. | Regulatory protein RecX; Modulates RecA activity; Belongs to the RecX family. | 0.794 |
| recA | dnaX | BSU16940 | BSU00190 | Multifunctional SOS repair factor; Multifunctional protein involved in homologous recombination, DNA repair and competence. Can catalyze the hydrolysis of (d)ATP in the presence of single-stranded DNA; prefers dATP at least in vitro, catalyzes the dATP-dependent uptake of single- stranded DNA by duplex DNA, and the dATP-dependent hybridization of homologous single-stranded DNAs (strand exchange). RecA-ATP cannot catalyze homologous DNA strand exchange; SsbA and DprA activate strand exchange by RecA-ATP. It interacts with LexA causing its activation and leading to its autocatalytic clea [...] | DNA polymerase III (gamma and tau subunits); DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. | 0.820 |
