node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
gpr | sigF | BSU25540 | BSU23450 | Germination protease; Initiates the degradation of small, acid-soluble proteins during spore germination | Rna polymerase sporulation-specific sigma factor (sigma-f); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of sporulation specific genes . Interaction with SpoIIAB inhibits sigma-F activity throughout the cell before the formation of the asymmetric septum; after septation the interaction is confined to the mother cell, and sigma F activity is released in the prespore. Responsible for expression of csfB (the anti-sigma-G factor Gin) | 0.934 |
gpr | sigG | BSU25540 | BSU15330 | Germination protease; Initiates the degradation of small, acid-soluble proteins during spore germination | Rna polymerase sporulation-specific sigma factor (sigma-g); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released . This sigma factor is responsible for the expression of sporulation specific genes in the forespore | 0.979 |
gpr | spo0A | BSU25540 | BSU24220 | Germination protease; Initiates the degradation of small, acid-soluble proteins during spore germination | Two-component system, response regulator, stage 0 sporulation protein a; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with Spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. Repressor of abrB, activator of the spoIIa operon. Binds the DNA sequence 5'-TGNCGAA-3' (0A box) | 0.805 |
gpr | spoIIID | BSU25540 | BSU36420 | Germination protease; Initiates the degradation of small, acid-soluble proteins during spore germination | Putative deor family transcriptional regulator, stage iii sporulation protein d; This protein regulates the transcription of sigK, which encodes mother cell chamber RNA polymerase sigma-factor (sigma K) | 0.854 |
gpr | spoIVA | BSU25540 | BSU22800 | Germination protease; Initiates the degradation of small, acid-soluble proteins during spore germination | Morphogenetic stage iv sporulation protein; ATPase. Has a role at an early stage in the morphogenesis of the spore coat outer layers. Its ATP hydrolysis is required for proper assembly of the spore coat. Forms a basement layer around the outside surface of the forespore and self-assembles irreversibly into higher order structures by binding and hydrolyzing ATP thus creating a durable and stable platform upon which thereafter morphogenesis of the coat can take place. Required for proper localization of spore coat protein CotE and sporulation-specific proteins including SpoVM | 0.888 |
gpr | spoVAD | BSU25540 | BSU23410 | Germination protease; Initiates the degradation of small, acid-soluble proteins during spore germination | Stage V sporulation protein AD; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type cp: cell process | 0.777 |
gpr | spoVT | BSU25540 | BSU00560 | Germination protease; Initiates the degradation of small, acid-soluble proteins during spore germination | Abrb family transcriptional regulator, stage v sporulation protein t; Transcriptional factor that regulates positively or negatively the expression of a large number of forespore-specific sigma G-dependent genes. May provide a mechanism of feedback control that is important for forespore development . SpoVT levels during spore formation have a major impact on the germination and the resistance of the resultant spores | 0.908 |
gpr | tepA | BSU25540 | BSU16790 | Germination protease; Initiates the degradation of small, acid-soluble proteins during spore germination | Translocation-enhancing protein tepa; Required for efficient translocation of pre-proteins across the membrane | 0.906 |
gpr | yabP | BSU25540 | BSU00600 | Germination protease; Initiates the degradation of small, acid-soluble proteins during spore germination | Spore protein involved in the shaping of the spore coat; Required for sporulation | 0.796 |
sigF | gpr | BSU23450 | BSU25540 | Rna polymerase sporulation-specific sigma factor (sigma-f); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of sporulation specific genes . Interaction with SpoIIAB inhibits sigma-F activity throughout the cell before the formation of the asymmetric septum; after septation the interaction is confined to the mother cell, and sigma F activity is released in the prespore. Responsible for expression of csfB (the anti-sigma-G factor Gin) | Germination protease; Initiates the degradation of small, acid-soluble proteins during spore germination | 0.934 |
sigF | spo0A | BSU23450 | BSU24220 | Rna polymerase sporulation-specific sigma factor (sigma-f); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of sporulation specific genes . Interaction with SpoIIAB inhibits sigma-F activity throughout the cell before the formation of the asymmetric septum; after septation the interaction is confined to the mother cell, and sigma F activity is released in the prespore. Responsible for expression of csfB (the anti-sigma-G factor Gin) | Two-component system, response regulator, stage 0 sporulation protein a; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with Spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. Repressor of abrB, activator of the spoIIa operon. Binds the DNA sequence 5'-TGNCGAA-3' (0A box) | 0.971 |
sigF | spoIIID | BSU23450 | BSU36420 | Rna polymerase sporulation-specific sigma factor (sigma-f); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of sporulation specific genes . Interaction with SpoIIAB inhibits sigma-F activity throughout the cell before the formation of the asymmetric septum; after septation the interaction is confined to the mother cell, and sigma F activity is released in the prespore. Responsible for expression of csfB (the anti-sigma-G factor Gin) | Putative deor family transcriptional regulator, stage iii sporulation protein d; This protein regulates the transcription of sigK, which encodes mother cell chamber RNA polymerase sigma-factor (sigma K) | 0.935 |
sigF | spoIVA | BSU23450 | BSU22800 | Rna polymerase sporulation-specific sigma factor (sigma-f); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of sporulation specific genes . Interaction with SpoIIAB inhibits sigma-F activity throughout the cell before the formation of the asymmetric septum; after septation the interaction is confined to the mother cell, and sigma F activity is released in the prespore. Responsible for expression of csfB (the anti-sigma-G factor Gin) | Morphogenetic stage iv sporulation protein; ATPase. Has a role at an early stage in the morphogenesis of the spore coat outer layers. Its ATP hydrolysis is required for proper assembly of the spore coat. Forms a basement layer around the outside surface of the forespore and self-assembles irreversibly into higher order structures by binding and hydrolyzing ATP thus creating a durable and stable platform upon which thereafter morphogenesis of the coat can take place. Required for proper localization of spore coat protein CotE and sporulation-specific proteins including SpoVM | 0.903 |
sigF | spoVAD | BSU23450 | BSU23410 | Rna polymerase sporulation-specific sigma factor (sigma-f); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of sporulation specific genes . Interaction with SpoIIAB inhibits sigma-F activity throughout the cell before the formation of the asymmetric septum; after septation the interaction is confined to the mother cell, and sigma F activity is released in the prespore. Responsible for expression of csfB (the anti-sigma-G factor Gin) | Stage V sporulation protein AD; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type cp: cell process | 0.893 |
sigF | spoVT | BSU23450 | BSU00560 | Rna polymerase sporulation-specific sigma factor (sigma-f); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of sporulation specific genes . Interaction with SpoIIAB inhibits sigma-F activity throughout the cell before the formation of the asymmetric septum; after septation the interaction is confined to the mother cell, and sigma F activity is released in the prespore. Responsible for expression of csfB (the anti-sigma-G factor Gin) | Abrb family transcriptional regulator, stage v sporulation protein t; Transcriptional factor that regulates positively or negatively the expression of a large number of forespore-specific sigma G-dependent genes. May provide a mechanism of feedback control that is important for forespore development . SpoVT levels during spore formation have a major impact on the germination and the resistance of the resultant spores | 0.891 |
sigF | tepA | BSU23450 | BSU16790 | Rna polymerase sporulation-specific sigma factor (sigma-f); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of sporulation specific genes . Interaction with SpoIIAB inhibits sigma-F activity throughout the cell before the formation of the asymmetric septum; after septation the interaction is confined to the mother cell, and sigma F activity is released in the prespore. Responsible for expression of csfB (the anti-sigma-G factor Gin) | Translocation-enhancing protein tepa; Required for efficient translocation of pre-proteins across the membrane | 0.647 |
sigF | yabP | BSU23450 | BSU00600 | Rna polymerase sporulation-specific sigma factor (sigma-f); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of sporulation specific genes . Interaction with SpoIIAB inhibits sigma-F activity throughout the cell before the formation of the asymmetric septum; after septation the interaction is confined to the mother cell, and sigma F activity is released in the prespore. Responsible for expression of csfB (the anti-sigma-G factor Gin) | Spore protein involved in the shaping of the spore coat; Required for sporulation | 0.754 |
sigG | gpr | BSU15330 | BSU25540 | Rna polymerase sporulation-specific sigma factor (sigma-g); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released . This sigma factor is responsible for the expression of sporulation specific genes in the forespore | Germination protease; Initiates the degradation of small, acid-soluble proteins during spore germination | 0.979 |
sigG | spo0A | BSU15330 | BSU24220 | Rna polymerase sporulation-specific sigma factor (sigma-g); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released . This sigma factor is responsible for the expression of sporulation specific genes in the forespore | Two-component system, response regulator, stage 0 sporulation protein a; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with Spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. Repressor of abrB, activator of the spoIIa operon. Binds the DNA sequence 5'-TGNCGAA-3' (0A box) | 0.988 |
sigG | spoIIID | BSU15330 | BSU36420 | Rna polymerase sporulation-specific sigma factor (sigma-g); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released . This sigma factor is responsible for the expression of sporulation specific genes in the forespore | Putative deor family transcriptional regulator, stage iii sporulation protein d; This protein regulates the transcription of sigK, which encodes mother cell chamber RNA polymerase sigma-factor (sigma K) | 0.984 |