| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| divIC | hslR | BSU00620 | BSU00590 | Cell-division initiation protein; Required for vegetative and sporulation septum formation. Required for the activation of genes expressed under the control of the sporulation transcription factors sigma F and sigma E. | Ribosomal RNA binding protein involved in 50S recycling; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; factor. | 0.750 |
| divIC | spoVT | BSU00620 | BSU00560 | Cell-division initiation protein; Required for vegetative and sporulation septum formation. Required for the activation of genes expressed under the control of the sporulation transcription factors sigma F and sigma E. | Transcriptional regulator; Transcriptional factor that regulates positively or negatively the expression of a large number of forespore-specific sigma G-dependent genes. May provide a mechanism of feedback control that is important for forespore development. SpoVT levels during spore formation have a major impact on the germination and the resistance of the resultant spores. To B.subtilis AbrB and Abh. | 0.585 |
| divIC | yabP | BSU00620 | BSU00600 | Cell-division initiation protein; Required for vegetative and sporulation septum formation. Required for the activation of genes expressed under the control of the sporulation transcription factors sigma F and sigma E. | Spore protein involved in the shaping of the spore coat; Required for sporulation. | 0.885 |
| divIC | yabQ | BSU00620 | BSU00610 | Cell-division initiation protein; Required for vegetative and sporulation septum formation. Required for the activation of genes expressed under the control of the sporulation transcription factors sigma F and sigma E. | Membrane protein of the forespore; Required for sporulation. Plays an important role in cortex and coat formation. | 0.870 |
| hslR | divIC | BSU00590 | BSU00620 | Ribosomal RNA binding protein involved in 50S recycling; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; factor. | Cell-division initiation protein; Required for vegetative and sporulation septum formation. Required for the activation of genes expressed under the control of the sporulation transcription factors sigma F and sigma E. | 0.750 |
| hslR | spoVT | BSU00590 | BSU00560 | Ribosomal RNA binding protein involved in 50S recycling; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; factor. | Transcriptional regulator; Transcriptional factor that regulates positively or negatively the expression of a large number of forespore-specific sigma G-dependent genes. May provide a mechanism of feedback control that is important for forespore development. SpoVT levels during spore formation have a major impact on the germination and the resistance of the resultant spores. To B.subtilis AbrB and Abh. | 0.657 |
| hslR | yabP | BSU00590 | BSU00600 | Ribosomal RNA binding protein involved in 50S recycling; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; factor. | Spore protein involved in the shaping of the spore coat; Required for sporulation. | 0.855 |
| hslR | yabQ | BSU00590 | BSU00610 | Ribosomal RNA binding protein involved in 50S recycling; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; factor. | Membrane protein of the forespore; Required for sporulation. Plays an important role in cortex and coat formation. | 0.854 |
| spoIIAB | spoIIID | BSU23460 | BSU36420 | Anti-sigma factor (antagonist of sigma(F)) and serine kinase; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. | Transcriptional regulator; This protein regulates the transcription of sigK, which encodes mother cell chamber RNA polymerase sigma-factor (sigma K). | 0.937 |
| spoIIAB | spoIIR | BSU23460 | BSU36970 | Anti-sigma factor (antagonist of sigma(F)) and serine kinase; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. | pro-sigma(E) endopeptidase (stage II sporulation); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme. | 0.982 |
| spoIIAB | spoVAF | BSU23460 | BSU23390 | Anti-sigma factor (antagonist of sigma(F)) and serine kinase; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. | Stage V sporulation protein AF; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type cp: cell process. | 0.918 |
| spoIIAB | spoVT | BSU23460 | BSU00560 | Anti-sigma factor (antagonist of sigma(F)) and serine kinase; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. | Transcriptional regulator; Transcriptional factor that regulates positively or negatively the expression of a large number of forespore-specific sigma G-dependent genes. May provide a mechanism of feedback control that is important for forespore development. SpoVT levels during spore formation have a major impact on the germination and the resistance of the resultant spores. To B.subtilis AbrB and Abh. | 0.908 |
| spoIIAB | yabP | BSU23460 | BSU00600 | Anti-sigma factor (antagonist of sigma(F)) and serine kinase; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. | Spore protein involved in the shaping of the spore coat; Required for sporulation. | 0.841 |
| spoIIAB | ylbJ | BSU23460 | BSU15030 | Anti-sigma factor (antagonist of sigma(F)) and serine kinase; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. | Putative factor required for spore cortex formation; Required for spore cortex formation. | 0.628 |
| spoIIAB | yqfD | BSU23460 | BSU25350 | Anti-sigma factor (antagonist of sigma(F)) and serine kinase; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. | Stage IV sporulation protein; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type cp: cell process. | 0.872 |
| spoIIID | spoIIAB | BSU36420 | BSU23460 | Transcriptional regulator; This protein regulates the transcription of sigK, which encodes mother cell chamber RNA polymerase sigma-factor (sigma K). | Anti-sigma factor (antagonist of sigma(F)) and serine kinase; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. | 0.937 |
| spoIIID | spoIIR | BSU36420 | BSU36970 | Transcriptional regulator; This protein regulates the transcription of sigK, which encodes mother cell chamber RNA polymerase sigma-factor (sigma K). | pro-sigma(E) endopeptidase (stage II sporulation); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme. | 0.955 |
| spoIIID | spoVAF | BSU36420 | BSU23390 | Transcriptional regulator; This protein regulates the transcription of sigK, which encodes mother cell chamber RNA polymerase sigma-factor (sigma K). | Stage V sporulation protein AF; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type cp: cell process. | 0.795 |
| spoIIID | spoVT | BSU36420 | BSU00560 | Transcriptional regulator; This protein regulates the transcription of sigK, which encodes mother cell chamber RNA polymerase sigma-factor (sigma K). | Transcriptional regulator; Transcriptional factor that regulates positively or negatively the expression of a large number of forespore-specific sigma G-dependent genes. May provide a mechanism of feedback control that is important for forespore development. SpoVT levels during spore formation have a major impact on the germination and the resistance of the resultant spores. To B.subtilis AbrB and Abh. | 0.980 |
| spoIIID | yabP | BSU36420 | BSU00600 | Transcriptional regulator; This protein regulates the transcription of sigK, which encodes mother cell chamber RNA polymerase sigma-factor (sigma K). | Spore protein involved in the shaping of the spore coat; Required for sporulation. | 0.848 |
