node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ctc | fusA | BSU00520 | BSU01120 | 50S ribosomal protein L25/general stress protein Ctc; Not required for exponential growth; probably functions in vegetatively growing cells, maybe required for accurate translation under stress conditions | Elongation factor g; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity) | 0.985 |
ctc | rplA | BSU00520 | BSU01030 | 50S ribosomal protein L25/general stress protein Ctc; Not required for exponential growth; probably functions in vegetatively growing cells, maybe required for accurate translation under stress conditions | Large subunit ribosomal protein l1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release | 0.999 |
ctc | rplD | BSU00520 | BSU01170 | 50S ribosomal protein L25/general stress protein Ctc; Not required for exponential growth; probably functions in vegetatively growing cells, maybe required for accurate translation under stress conditions | Large subunit ribosomal protein l4; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome | 0.999 |
ctc | rplJ | BSU00520 | BSU01040 | 50S ribosomal protein L25/general stress protein Ctc; Not required for exponential growth; probably functions in vegetatively growing cells, maybe required for accurate translation under stress conditions | Large subunit ribosomal protein l10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors (such as IF-2, EF-Tu, EF-G and RF3) | 0.999 |
ctc | rplK | BSU00520 | BSU01020 | 50S ribosomal protein L25/general stress protein Ctc; Not required for exponential growth; probably functions in vegetatively growing cells, maybe required for accurate translation under stress conditions | Large subunit ribosomal protein l11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors | 0.999 |
ctc | rplL | BSU00520 | BSU01050 | 50S ribosomal protein L25/general stress protein Ctc; Not required for exponential growth; probably functions in vegetatively growing cells, maybe required for accurate translation under stress conditions | Large subunit ribosomal protein l7/l12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation | 0.997 |
ctc | rpsG | BSU00520 | BSU01110 | 50S ribosomal protein L25/general stress protein Ctc; Not required for exponential growth; probably functions in vegetatively growing cells, maybe required for accurate translation under stress conditions | Small subunit ribosomal protein s7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA | 0.999 |
ctc | rpsJ | BSU00520 | BSU01150 | 50S ribosomal protein L25/general stress protein Ctc; Not required for exponential growth; probably functions in vegetatively growing cells, maybe required for accurate translation under stress conditions | Small subunit ribosomal protein s10; Involved in the binding of tRNA to the ribosomes | 0.999 |
ctc | rpsL | BSU00520 | BSU01100 | 50S ribosomal protein L25/general stress protein Ctc; Not required for exponential growth; probably functions in vegetatively growing cells, maybe required for accurate translation under stress conditions | Small subunit ribosomal protein s12; With S4 and S5 plays an important role in translational accuracy | 0.998 |
fusA | ctc | BSU01120 | BSU00520 | Elongation factor g; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity) | 50S ribosomal protein L25/general stress protein Ctc; Not required for exponential growth; probably functions in vegetatively growing cells, maybe required for accurate translation under stress conditions | 0.985 |
fusA | gltX | BSU01120 | BSU00920 | Elongation factor g; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity) | Nondiscriminating glutamyl-trna synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) | 0.973 |
fusA | rplA | BSU01120 | BSU01030 | Elongation factor g; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity) | Large subunit ribosomal protein l1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release | 0.999 |
fusA | rplD | BSU01120 | BSU01170 | Elongation factor g; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity) | Large subunit ribosomal protein l4; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome | 0.999 |
fusA | rplJ | BSU01120 | BSU01040 | Elongation factor g; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity) | Large subunit ribosomal protein l10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors (such as IF-2, EF-Tu, EF-G and RF3) | 0.998 |
fusA | rplK | BSU01120 | BSU01020 | Elongation factor g; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity) | Large subunit ribosomal protein l11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors | 0.999 |
fusA | rplL | BSU01120 | BSU01050 | Elongation factor g; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity) | Large subunit ribosomal protein l7/l12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation | 0.984 |
fusA | rpsG | BSU01120 | BSU01110 | Elongation factor g; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity) | Small subunit ribosomal protein s7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA | 0.999 |
fusA | rpsJ | BSU01120 | BSU01150 | Elongation factor g; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity) | Small subunit ribosomal protein s10; Involved in the binding of tRNA to the ribosomes | 0.999 |
fusA | rpsL | BSU01120 | BSU01100 | Elongation factor g; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity) | Small subunit ribosomal protein s12; With S4 and S5 plays an important role in translational accuracy | 0.999 |
gltX | fusA | BSU00920 | BSU01120 | Nondiscriminating glutamyl-trna synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) | Elongation factor g; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity) | 0.973 |