node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
adaA | adaB | BSU01810 | BSU01820 | Arac family transcriptional regulator, regulatory protein of adaptative response / methylphosphotriester-dna alkyltransferase methyltransferase; Is involved in the adaptive response to alkylation damage in DNA caused by alkylating agents. Repairs the methylphosphotriester lesions in DNA by a direct and irreversible transfer of the methyl group to one of its own cysteine residues | Methylated-dna-[protein]-cysteine s-methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated | 0.999 |
adaA | ndhF | BSU01810 | BSU01830 | Arac family transcriptional regulator, regulatory protein of adaptative response / methylphosphotriester-dna alkyltransferase methyltransferase; Is involved in the adaptive response to alkylation damage in DNA caused by alkylating agents. Repairs the methylphosphotriester lesions in DNA by a direct and irreversible transfer of the methyl group to one of its own cysteine residues | Nad(p)h-quinone oxidoreductase subunit 5; Belongs to the complex I subunit 5 family | 0.729 |
adaB | adaA | BSU01820 | BSU01810 | Methylated-dna-[protein]-cysteine s-methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated | Arac family transcriptional regulator, regulatory protein of adaptative response / methylphosphotriester-dna alkyltransferase methyltransferase; Is involved in the adaptive response to alkylation damage in DNA caused by alkylating agents. Repairs the methylphosphotriester lesions in DNA by a direct and irreversible transfer of the methyl group to one of its own cysteine residues | 0.999 |
adaB | ndhF | BSU01820 | BSU01830 | Methylated-dna-[protein]-cysteine s-methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated | Nad(p)h-quinone oxidoreductase subunit 5; Belongs to the complex I subunit 5 family | 0.659 |
mrpB | mrpD | BSU31610 | BSU31630 | Multicomponent na+:h+ antiporter subunit b; Mrp complex is a Na(+)/H(+) antiporter that is considered to be the major Na(+) excretion system in B.subtilis. Has a major role in Na(+) resistance and a minor role in Na(+)- and K(+)-dependent pH homeostasis as compared to TetB. MrpA may be the actual Na(+)/H(+) antiporter, although the six other Mrp proteins are all required for Na(+)/H(+) antiport activity and Na(+) resistance. MrpA is required for initiation of sporulation when external Na(+) concentration increases. Also transports Li(+) but not K(+), Ca(2+) or Mg(2+) | Proton transporter component of na+/h+ antiporter; Mrp complex is a Na(+)/H(+) antiporter that is considered to be the major Na(+) excretion system in B.subtilis. Has a major role in Na(+) resistance and a minor role in Na(+)- and K(+)-dependent pH homeostasis as compared to TetB. MrpA may be the actual Na(+)/H(+) antiporter, although the six other Mrp proteins are all required for Na(+)/H(+) antiport activity and Na(+) resistance. MrpA is required for initiation of sporulation when external Na(+) concentration increases. Also transports Li(+) but not K(+), Ca(2+) or Mg(2+) | 0.999 |
mrpB | ndhF | BSU31610 | BSU01830 | Multicomponent na+:h+ antiporter subunit b; Mrp complex is a Na(+)/H(+) antiporter that is considered to be the major Na(+) excretion system in B.subtilis. Has a major role in Na(+) resistance and a minor role in Na(+)- and K(+)-dependent pH homeostasis as compared to TetB. MrpA may be the actual Na(+)/H(+) antiporter, although the six other Mrp proteins are all required for Na(+)/H(+) antiport activity and Na(+) resistance. MrpA is required for initiation of sporulation when external Na(+) concentration increases. Also transports Li(+) but not K(+), Ca(2+) or Mg(2+) | Nad(p)h-quinone oxidoreductase subunit 5; Belongs to the complex I subunit 5 family | 0.843 |
mrpD | mrpB | BSU31630 | BSU31610 | Proton transporter component of na+/h+ antiporter; Mrp complex is a Na(+)/H(+) antiporter that is considered to be the major Na(+) excretion system in B.subtilis. Has a major role in Na(+) resistance and a minor role in Na(+)- and K(+)-dependent pH homeostasis as compared to TetB. MrpA may be the actual Na(+)/H(+) antiporter, although the six other Mrp proteins are all required for Na(+)/H(+) antiport activity and Na(+) resistance. MrpA is required for initiation of sporulation when external Na(+) concentration increases. Also transports Li(+) but not K(+), Ca(2+) or Mg(2+) | Multicomponent na+:h+ antiporter subunit b; Mrp complex is a Na(+)/H(+) antiporter that is considered to be the major Na(+) excretion system in B.subtilis. Has a major role in Na(+) resistance and a minor role in Na(+)- and K(+)-dependent pH homeostasis as compared to TetB. MrpA may be the actual Na(+)/H(+) antiporter, although the six other Mrp proteins are all required for Na(+)/H(+) antiport activity and Na(+) resistance. MrpA is required for initiation of sporulation when external Na(+) concentration increases. Also transports Li(+) but not K(+), Ca(2+) or Mg(2+) | 0.999 |
mrpD | ndhF | BSU31630 | BSU01830 | Proton transporter component of na+/h+ antiporter; Mrp complex is a Na(+)/H(+) antiporter that is considered to be the major Na(+) excretion system in B.subtilis. Has a major role in Na(+) resistance and a minor role in Na(+)- and K(+)-dependent pH homeostasis as compared to TetB. MrpA may be the actual Na(+)/H(+) antiporter, although the six other Mrp proteins are all required for Na(+)/H(+) antiport activity and Na(+) resistance. MrpA is required for initiation of sporulation when external Na(+) concentration increases. Also transports Li(+) but not K(+), Ca(2+) or Mg(2+) | Nad(p)h-quinone oxidoreductase subunit 5; Belongs to the complex I subunit 5 family | 0.902 |
ndh | ndhF | BSU12290 | BSU01830 | Nadh:ubiquinone reductase (h+-translocating); Belongs to the NADH dehydrogenase family | Nad(p)h-quinone oxidoreductase subunit 5; Belongs to the complex I subunit 5 family | 0.813 |
ndh | yumB | BSU12290 | BSU32100 | Nadh:ubiquinone reductase (h+-translocating); Belongs to the NADH dehydrogenase family | Nadh:ubiquinone reductase (h+-translocating); NADH dehydrogenase-like protein YumB; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme | 0.821 |
ndh | yutJ | BSU12290 | BSU32200 | Nadh:ubiquinone reductase (h+-translocating); Belongs to the NADH dehydrogenase family | Nadh:ubiquinone reductase (h+-translocating); NADH dehydrogenase-like protein YutJ; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme | 0.830 |
ndhF | adaA | BSU01830 | BSU01810 | Nad(p)h-quinone oxidoreductase subunit 5; Belongs to the complex I subunit 5 family | Arac family transcriptional regulator, regulatory protein of adaptative response / methylphosphotriester-dna alkyltransferase methyltransferase; Is involved in the adaptive response to alkylation damage in DNA caused by alkylating agents. Repairs the methylphosphotriester lesions in DNA by a direct and irreversible transfer of the methyl group to one of its own cysteine residues | 0.729 |
ndhF | adaB | BSU01830 | BSU01820 | Nad(p)h-quinone oxidoreductase subunit 5; Belongs to the complex I subunit 5 family | Methylated-dna-[protein]-cysteine s-methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated | 0.659 |
ndhF | mrpB | BSU01830 | BSU31610 | Nad(p)h-quinone oxidoreductase subunit 5; Belongs to the complex I subunit 5 family | Multicomponent na+:h+ antiporter subunit b; Mrp complex is a Na(+)/H(+) antiporter that is considered to be the major Na(+) excretion system in B.subtilis. Has a major role in Na(+) resistance and a minor role in Na(+)- and K(+)-dependent pH homeostasis as compared to TetB. MrpA may be the actual Na(+)/H(+) antiporter, although the six other Mrp proteins are all required for Na(+)/H(+) antiport activity and Na(+) resistance. MrpA is required for initiation of sporulation when external Na(+) concentration increases. Also transports Li(+) but not K(+), Ca(2+) or Mg(2+) | 0.843 |
ndhF | mrpD | BSU01830 | BSU31630 | Nad(p)h-quinone oxidoreductase subunit 5; Belongs to the complex I subunit 5 family | Proton transporter component of na+/h+ antiporter; Mrp complex is a Na(+)/H(+) antiporter that is considered to be the major Na(+) excretion system in B.subtilis. Has a major role in Na(+) resistance and a minor role in Na(+)- and K(+)-dependent pH homeostasis as compared to TetB. MrpA may be the actual Na(+)/H(+) antiporter, although the six other Mrp proteins are all required for Na(+)/H(+) antiport activity and Na(+) resistance. MrpA is required for initiation of sporulation when external Na(+) concentration increases. Also transports Li(+) but not K(+), Ca(2+) or Mg(2+) | 0.902 |
ndhF | ndh | BSU01830 | BSU12290 | Nad(p)h-quinone oxidoreductase subunit 5; Belongs to the complex I subunit 5 family | Nadh:ubiquinone reductase (h+-translocating); Belongs to the NADH dehydrogenase family | 0.813 |
ndhF | ybcC | BSU01830 | BSU01845 | Nad(p)h-quinone oxidoreductase subunit 5; Belongs to the complex I subunit 5 family | Conserved hypothetical protein; Belongs to the UPF0753 family | 0.985 |
ndhF | ybcF | BSU01830 | BSU01860 | Nad(p)h-quinone oxidoreductase subunit 5; Belongs to the complex I subunit 5 family | Carbonic anhydrase-like protein ybcf; Belongs to the beta-class carbonic anhydrase family | 0.657 |
ndhF | ybcI | BSU01830 | BSU01880 | Nad(p)h-quinone oxidoreductase subunit 5; Belongs to the complex I subunit 5 family | Conserved hypothetical protein; Uncharacterized protein YbcI; Evidence 4: Homologs of previously reported genes of unknown function | 0.908 |
ndhF | yumB | BSU01830 | BSU32100 | Nad(p)h-quinone oxidoreductase subunit 5; Belongs to the complex I subunit 5 family | Nadh:ubiquinone reductase (h+-translocating); NADH dehydrogenase-like protein YumB; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme | 0.813 |