STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ndhFNad(p)h-quinone oxidoreductase subunit 5; Belongs to the complex I subunit 5 family (505 aa)    
Predicted Functional Partners:
ybcC
Conserved hypothetical protein; Belongs to the UPF0753 family
    0.985
ybcI
Conserved hypothetical protein; Uncharacterized protein YbcI; Evidence 4: Homologs of previously reported genes of unknown function
 
    0.908
mrpD
Proton transporter component of na+/h+ antiporter; Mrp complex is a Na(+)/H(+) antiporter that is considered to be the major Na(+) excretion system in B.subtilis. Has a major role in Na(+) resistance and a minor role in Na(+)- and K(+)-dependent pH homeostasis as compared to TetB. MrpA may be the actual Na(+)/H(+) antiporter, although the six other Mrp proteins are all required for Na(+)/H(+) antiport activity and Na(+) resistance. MrpA is required for initiation of sporulation when external Na(+) concentration increases. Also transports Li(+) but not K(+), Ca(2+) or Mg(2+)
 
 
 0.902
mrpB
Multicomponent na+:h+ antiporter subunit b; Mrp complex is a Na(+)/H(+) antiporter that is considered to be the major Na(+) excretion system in B.subtilis. Has a major role in Na(+) resistance and a minor role in Na(+)- and K(+)-dependent pH homeostasis as compared to TetB. MrpA may be the actual Na(+)/H(+) antiporter, although the six other Mrp proteins are all required for Na(+)/H(+) antiport activity and Na(+) resistance. MrpA is required for initiation of sporulation when external Na(+) concentration increases. Also transports Li(+) but not K(+), Ca(2+) or Mg(2+)
 
 0.843
ndh
Nadh:ubiquinone reductase (h+-translocating); Belongs to the NADH dehydrogenase family
    
 0.813
yumB
Nadh:ubiquinone reductase (h+-translocating); NADH dehydrogenase-like protein YumB; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme
    
 0.813
yutJ
Nadh:ubiquinone reductase (h+-translocating); NADH dehydrogenase-like protein YutJ; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
    
 0.813
adaA
Arac family transcriptional regulator, regulatory protein of adaptative response / methylphosphotriester-dna alkyltransferase methyltransferase; Is involved in the adaptive response to alkylation damage in DNA caused by alkylating agents. Repairs the methylphosphotriester lesions in DNA by a direct and irreversible transfer of the methyl group to one of its own cysteine residues
      
 0.729
adaB
Methylated-dna-[protein]-cysteine s-methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated
      
 0.659
ybcF
Carbonic anhydrase-like protein ybcf; Belongs to the beta-class carbonic anhydrase family
     
 0.657
Your Current Organism:
Bacillus subtilis
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
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