STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ybdKTwo-component sensor histidine kinase [YbdJ]; Member of the two-component regulatory system YbdK/YbdJ. Probably activates YbdJ by phosphorylation. (320 aa)    
Predicted Functional Partners:
ybdJ
Two-component response regulator [YbdK]; Member of the two-component regulatory system YbdK/YbdJ.
 
 
 0.984
ybdG
Putative hydrolase/transferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
 
   0.829
yeaA
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
      
 0.802
yvlA
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
      
 0.750
yvlB
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
      
 0.748
ymcC
Putative integral inner membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane component.
      
 0.745
fin
Protein required for the switch from F to G during sporulation (anti sigma F); An anti-sigma factor for sporulation specific sigma-F factor, by antagonizing sigma-F it allows the switch to sigma-G factor and progression to the late sporulation development stages. Might stabilize or process Holliday junction intermediates, although this may be due to polar effects on the downstream mfd gene.
      
 0.681
rbsB
Ribose ABC transporter (ribose-binding lipoprotein); Part of the ABC transporter complex RbsABC involved in ribose import. Binds ribose.
    
 
 0.598
ybzI
Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
  
    0.596
yuaF
Putative membrane integrity integral membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane component.
   
  
 0.578
Your Current Organism:
Bacillus subtilis 168
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
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