STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ybyBConserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. (86 aa)    
Predicted Functional Partners:
ywzA
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
   
  
 0.788
yfkM
General stress protein 18; Functions in the protection against aldehyde-stress, possibly by degrading damaged proteins.
   
  
 0.779
csbD
Conserved hypothetical protein; Evidence 7: Gene remnant.
  
  
 0.763
nhaX
Stress response protein, UspA family; Evidence 2b: Function of strongly homologous gene; factor.
   
  
 0.728
rsbW
Switch protein/serine kinase and anti-sigma factor (inhibitory sigma-B binding protein); Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B).
  
  
 0.726
ykzI
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
   
    0.725
ywjC
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
   
  
 0.724
ykgA
Putative aminohydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the DDAH family.
   
  
 0.703
csbC
Putative sugar transporter; Could serve either a nutritional or an osmotic protection function; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
   
  
 0.693
yflT
Heat stress induced protein; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type f: factor.
   
  
 0.683
Your Current Organism:
Bacillus subtilis 168
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
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