STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ybyBConserved hypothetical protein; Uncharacterized protein YbyB; Evidence 4: Homologs of previously reported genes of unknown function (86 aa)    
Predicted Functional Partners:
yjbC
Putative thiol oxidation management factor; Putative acetyltransferase YjbC; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme
  
     0.668
ysdB
Conserved hypothetical protein; May mediate a negative feedback loop that down-regulates the expression of the sigma-W regulon following the activation of sigma-W in response to conditions of cell envelope stress. Might interact with and inhibit the activity of the protease PrsW, or could bind to the anti-sigma-W factor RsiW and thereby protect it from PrsW-mediated cleavage
  
     0.637
yolD
SPBc2 prophage-derived uncharacterized protein YolD; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 12137951
  
     0.610
splA
Regulator of the spore photoproduct lyase operon (splAB)
  
     0.552
ywlB
Conserved hypothetical protein; Uncharacterized protein YwlB; Evidence 4: Homologs of previously reported genes of unknown function
  
     0.537
ykyA
Uncharacterized lipoprotein YkyA; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor
  
     0.533
ipi
Intracellular proteinase inhibitor bsupi; Directly regulates the major intracellular proteinase (ISP-1) activity in vivo. Inhibits ISP-1 in the early stages of sporulation. It may be then inactivated by a membrane-bound proteinase
  
     0.522
yvlB
Conserved hypothetical protein; Uncharacterized protein YvlB; Evidence 4: Homologs of previously reported genes of unknown function
  
     0.515
yqgU
Uncharacterized lipoprotein YqgU; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp: lipoprotein
  
     0.509
yycD
Conserved hypothetical protein; Uncharacterized protein YycD; Evidence 4: Homologs of previously reported genes of unknown function
  
     0.476
Your Current Organism:
Bacillus subtilis
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.