node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ansZ | lmrA | BSU02690 | BSU02680 | L-asparaginase 2 (putative lipoprotein); Catalyzes the conversion of L-asparagine to L-aspartate and ammonium. | Transcriptional repressor of lmrAB and yxaGH operons; Acts as repressor of the lincomycin-resistance (lmrAB) and yxaGH operons. | 0.554 |
ansZ | lmrB | BSU02690 | BSU02670 | L-asparaginase 2 (putative lipoprotein); Catalyzes the conversion of L-asparagine to L-aspartate and ammonium. | Efflux transporter; Proton-dependent transporter. May mediate the efflux of lincomycin; Belongs to the major facilitator superfamily. EmrB family. | 0.518 |
ansZ | yccK | BSU02690 | BSU02770 | L-asparaginase 2 (putative lipoprotein); Catalyzes the conversion of L-asparagine to L-aspartate and ammonium. | Putative ion channel associated enzyme; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the aldo/keto reductase family. Aldo/keto reductase 2 subfamily. | 0.487 |
bmrA | lmrA | BSU34820 | BSU02680 | Efflux transporter (ATP-binding and permease protein); An efflux transporter able to transport Hoechst 33342, ethidium bromide, doxorubicin and a number of other drugs in vitro into inside out vesicles. The endogenous substrate is unknown. It has been suggested that NBD dimerization induced by ATP-binding causes a large conformational change responsible for substrate translocation. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (Probable). | Transcriptional repressor of lmrAB and yxaGH operons; Acts as repressor of the lincomycin-resistance (lmrAB) and yxaGH operons. | 0.978 |
bmrA | tmrB | BSU34820 | BSU03140 | Efflux transporter (ATP-binding and permease protein); An efflux transporter able to transport Hoechst 33342, ethidium bromide, doxorubicin and a number of other drugs in vitro into inside out vesicles. The endogenous substrate is unknown. It has been suggested that NBD dimerization induced by ATP-binding causes a large conformational change responsible for substrate translocation. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (Probable). | ATP-binding tunicamycin resistance protein; Involved in the resistance to tunicamycin. Binds ATP. | 0.560 |
cgeA | lmrA | BSU19780 | BSU02680 | Spore outermost layer component; May be involved in maturation of the outermost layer of the spore. | Transcriptional repressor of lmrAB and yxaGH operons; Acts as repressor of the lincomycin-resistance (lmrAB) and yxaGH operons. | 0.481 |
lmrA | ansZ | BSU02680 | BSU02690 | Transcriptional repressor of lmrAB and yxaGH operons; Acts as repressor of the lincomycin-resistance (lmrAB) and yxaGH operons. | L-asparaginase 2 (putative lipoprotein); Catalyzes the conversion of L-asparagine to L-aspartate and ammonium. | 0.554 |
lmrA | bmrA | BSU02680 | BSU34820 | Transcriptional repressor of lmrAB and yxaGH operons; Acts as repressor of the lincomycin-resistance (lmrAB) and yxaGH operons. | Efflux transporter (ATP-binding and permease protein); An efflux transporter able to transport Hoechst 33342, ethidium bromide, doxorubicin and a number of other drugs in vitro into inside out vesicles. The endogenous substrate is unknown. It has been suggested that NBD dimerization induced by ATP-binding causes a large conformational change responsible for substrate translocation. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (Probable). | 0.978 |
lmrA | cgeA | BSU02680 | BSU19780 | Transcriptional repressor of lmrAB and yxaGH operons; Acts as repressor of the lincomycin-resistance (lmrAB) and yxaGH operons. | Spore outermost layer component; May be involved in maturation of the outermost layer of the spore. | 0.481 |
lmrA | lmrB | BSU02680 | BSU02670 | Transcriptional repressor of lmrAB and yxaGH operons; Acts as repressor of the lincomycin-resistance (lmrAB) and yxaGH operons. | Efflux transporter; Proton-dependent transporter. May mediate the efflux of lincomycin; Belongs to the major facilitator superfamily. EmrB family. | 0.991 |
lmrA | mntA | BSU02680 | BSU30770 | Transcriptional repressor of lmrAB and yxaGH operons; Acts as repressor of the lincomycin-resistance (lmrAB) and yxaGH operons. | Manganese ABC transporter (manganese binding lipoprotein); Probably part of the ABC transporter complex MntABCD involved in manganese import. | 0.681 |
lmrA | qodI | BSU02680 | BSU39980 | Transcriptional repressor of lmrAB and yxaGH operons; Acts as repressor of the lincomycin-resistance (lmrAB) and yxaGH operons. | Quercetin dioxygenase; Performs the first step in the degradation of the flavonoid quercetin by a dioxygenase reaction. The enzyme catalyzes the cleavage of the O-heteroaromatic ring of the flavonol quercetin yielding the depside 2-protocatechuoyl-phloroglucinol carboxylic acid and carbon monoxide. This involves the remarkable dioxygenolytic cleavage of two carbon-carbon bonds. | 0.698 |
lmrA | tmrB | BSU02680 | BSU03140 | Transcriptional repressor of lmrAB and yxaGH operons; Acts as repressor of the lincomycin-resistance (lmrAB) and yxaGH operons. | ATP-binding tunicamycin resistance protein; Involved in the resistance to tunicamycin. Binds ATP. | 0.487 |
lmrA | xynA | BSU02680 | BSU18840 | Transcriptional repressor of lmrAB and yxaGH operons; Acts as repressor of the lincomycin-resistance (lmrAB) and yxaGH operons. | Endo-1,4-beta-xylanase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the glycosyl hydrolase 11 (cellulase G) family. | 0.480 |
lmrA | yccK | BSU02680 | BSU02770 | Transcriptional repressor of lmrAB and yxaGH operons; Acts as repressor of the lincomycin-resistance (lmrAB) and yxaGH operons. | Putative ion channel associated enzyme; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the aldo/keto reductase family. Aldo/keto reductase 2 subfamily. | 0.487 |
lmrA | ycnK | BSU02680 | BSU03960 | Transcriptional repressor of lmrAB and yxaGH operons; Acts as repressor of the lincomycin-resistance (lmrAB) and yxaGH operons. | Putative transcriptional regulator (DeoR family); May act as a negative transcriptional regulator of ycnJ in the presence of copper. May use copper as a corepressor. | 0.483 |
lmrB | ansZ | BSU02670 | BSU02690 | Efflux transporter; Proton-dependent transporter. May mediate the efflux of lincomycin; Belongs to the major facilitator superfamily. EmrB family. | L-asparaginase 2 (putative lipoprotein); Catalyzes the conversion of L-asparagine to L-aspartate and ammonium. | 0.518 |
lmrB | lmrA | BSU02670 | BSU02680 | Efflux transporter; Proton-dependent transporter. May mediate the efflux of lincomycin; Belongs to the major facilitator superfamily. EmrB family. | Transcriptional repressor of lmrAB and yxaGH operons; Acts as repressor of the lincomycin-resistance (lmrAB) and yxaGH operons. | 0.991 |
lmrB | qodI | BSU02670 | BSU39980 | Efflux transporter; Proton-dependent transporter. May mediate the efflux of lincomycin; Belongs to the major facilitator superfamily. EmrB family. | Quercetin dioxygenase; Performs the first step in the degradation of the flavonoid quercetin by a dioxygenase reaction. The enzyme catalyzes the cleavage of the O-heteroaromatic ring of the flavonol quercetin yielding the depside 2-protocatechuoyl-phloroglucinol carboxylic acid and carbon monoxide. This involves the remarkable dioxygenolytic cleavage of two carbon-carbon bonds. | 0.503 |
lmrB | yccK | BSU02670 | BSU02770 | Efflux transporter; Proton-dependent transporter. May mediate the efflux of lincomycin; Belongs to the major facilitator superfamily. EmrB family. | Putative ion channel associated enzyme; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the aldo/keto reductase family. Aldo/keto reductase 2 subfamily. | 0.634 |