STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
estASecreted alkaliphilic lipase; Active toward p-nitrophenyl esters and triacylglycerides with a marked preference for esters with C8 acyl groups. Belongs to the AB hydrolase superfamily. (212 aa)    
Predicted Functional Partners:
ydeN
Alpha/beta hydrolase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the RBBP9 family.
      
 0.980
estB
Secreted esterase / lipase; An esterase which preferentially hydrolyzes triacylglyceride substrates with short chain fatty acids (less than C10) with the maximum activity towards tricaprylin (C8:0). Active against p- nitrophenylesters with fatty acid chain lengths from C6 to C18.
  
 
0.907
dagK
Diacylglycerol kinase; Catalyzes the phosphorylation of diacylglycerol (DAG) into phosphatidic acid. Is a key enzyme involved in the production of lipoteichoic acid by reintroducing DAG formed from the breakdown of membrane phospholipids into the phosphatidylglycerol biosynthetic pathway. Is more active toward long-chain DAG compared with short-chain DAG. Is not able to phosphorylate substrates other than DAG, such as monoacylglycerol, ceramide, undecaprenol, phosphatidylinositol, or sphingosine; Belongs to the diacylglycerol/lipid kinase family.
     
 0.905
ugtP
UDP-glucose diacylglyceroltransferase; Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta- monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl-sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1->6)-D- glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta-triglucosyl-DAG (3-O- (beta-D-glucopyranosyl-beta-(1->6)-D-glucopyranosyl-beta-(1->6)-D- glucopyranosyl)-1,2-diac [...]
     
  0.900
nap
Carboxylesterase NP; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the AB hydrolase superfamily.
  
  
 0.881
bslA
Biofilm hydrophobic layer component; Involved in biofilm formation. Self-polymerizes and forms a layer on the surface of biofilms that confers hydrophobicity to the biofilm. The layer is stable and capable of resistance to high mechanical force compression. Required for complex colony architecture. May function synergistically with exopolysaccharides and TasA amyloid fibers to facilitate the assembly of the biofilm matrix.
  
  
 0.860
yvaK
Carboxylesterase; Involved in the detoxification of xenobiotics. Shows maximal activity with C6 substrates, with gradually decreasing activity from C8 to C12 substrates. No activity for higher chain length substrates acids rather than long-chain ones (By similarity).
      
 0.847
yhfT
Putative long-chain fatty-acid-CoA ligase; May be involved in fatty acid metabolism; Belongs to the ATP-dependent AMP-binding enzyme family.
   
 
  0.801
lcfB
Long-chain fatty-acid-CoA ligase (degradative); Involved in the degradation of long-chain fatty acids; Belongs to the ATP-dependent AMP-binding enzyme family.
     
  0.800
lcfA
Long chain acyl-CoA ligase (degradative); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme.
     
  0.800
Your Current Organism:
Bacillus subtilis 168
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
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