STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yccKPutative ion channel associated enzyme; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the aldo/keto reductase family. Aldo/keto reductase 2 subfamily. (310 aa)    
Predicted Functional Partners:
yugT
Putative oligo-1,6-glucosidase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the glycosyl hydrolase 13 family.
   
  
 0.712
lmrB
Efflux transporter; Proton-dependent transporter. May mediate the efflux of lincomycin; Belongs to the major facilitator superfamily. EmrB family.
      
 0.634
ansA
Exported L-asparaginase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the asparaginase 1 family.
      
 0.632
pksJ
Polyketide synthase of type I; Involved in some intermediate steps for the synthesis of the antibiotic polyketide bacillaene which is involved in secondary metabolism.
  
 0.517
natB
Na+ ABC efflux transporter (permease); Part of an ABC transporter that catalyzes ATP-dependent electrogenic sodium extrusion.
  
    0.495
natA
Na+ ABC efflux transporter (ATP-binding protein); Part of an ABC transporter that catalyzes ATP-dependent electrogenic sodium extrusion; Belongs to the ABC transporter superfamily.
  
    0.489
lmrA
Transcriptional repressor of lmrAB and yxaGH operons; Acts as repressor of the lincomycin-resistance (lmrAB) and yxaGH operons.
      
 0.487
ansZ
L-asparaginase 2 (putative lipoprotein); Catalyzes the conversion of L-asparagine to L-aspartate and ammonium.
      
 0.487
ybbK
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
   
  
 0.485
yjzH
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
      
 0.479
Your Current Organism:
Bacillus subtilis 168
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
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