STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nasCAssimilatory nitrate reductase (catalytic subunit); Nitrate reductase is a key enzyme involved in the first step of nitrate assimilation in plants, fungi and bacteria. (710 aa)    
Predicted Functional Partners:
nasD
Assimilatory nitrite reductase subunit; Required for nitrite assimilation.
 
 0.999
nasB
Assimilatory nitrate reductase (electron transfer subunit NasB); Required for nitrate assimilation.
 
 0.999
nasA
Putative nitrate transporter; May function as a nitrate transporter.
 
 
 0.994
nasE
Assimilatory nitrite reductase subunit; Required for nitrite assimilation. Required for activity of the reductase (By similarity).
 
 
 0.993
narK
Nitrite extrusion permease; Involved in excretion of nitrite produced by the dissimilatory reduction of nitrate; Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
 
  
 0.986
cysJ
Sulfite reductase (flavoprotein alpha-subunit); Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component (Probable).
    
 0.976
narI
Nitrate reductase (gamma subunit); The gamma chain is a membrane-embedded heme-iron unit resembling cytochrome b, which transfers electrons from quinones to the beta subunit.
     
 0.947
narH
Nitrate reductase (beta subunit); The beta chain is an electron transfer unit containing four cysteine clusters involved in the formation of iron-sulfur centers. Electrons are transferred from the gamma chain to the molybdenum cofactor of the alpha subunit.
   
 
 0.946
narG
Nitrate reductase (alpha subunit); The alpha chain is the actual site of nitrate reduction.
   
 
0.932
gltB
Glutamate synthase (small subunit); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme.
    
 0.923
Your Current Organism:
Bacillus subtilis 168
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
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