STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nasAPutative nitrate transporter; May function as a nitrate transporter. (401 aa)    
Predicted Functional Partners:
narG
Nitrate reductase (alpha subunit); The alpha chain is the actual site of nitrate reduction.
 
 
 0.996
nasC
Assimilatory nitrate reductase (catalytic subunit); Nitrate reductase is a key enzyme involved in the first step of nitrate assimilation in plants, fungi and bacteria.
 
 
 0.994
nasB
Assimilatory nitrate reductase (electron transfer subunit NasB); Required for nitrate assimilation.
 
 
 0.994
narH
Nitrate reductase (beta subunit); The beta chain is an electron transfer unit containing four cysteine clusters involved in the formation of iron-sulfur centers. Electrons are transferred from the gamma chain to the molybdenum cofactor of the alpha subunit.
 
 
 0.991
nasD
Assimilatory nitrite reductase subunit; Required for nitrite assimilation.
 
 
 0.990
nasE
Assimilatory nitrite reductase subunit; Required for nitrite assimilation. Required for activity of the reductase (By similarity).
 
 
 0.986
narI
Nitrate reductase (gamma subunit); The gamma chain is a membrane-embedded heme-iron unit resembling cytochrome b, which transfers electrons from quinones to the beta subunit.
 
 
 0.983
narK
Nitrite extrusion permease; Involved in excretion of nitrite produced by the dissimilatory reduction of nitrate; Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
  
 
0.931
amtB
Ammonium transporter; Functions as an ammonium and methylammonium transporter in the absence of glutamine. Required for ammonium utilization at low concentrations or at low pH values, when ammonium is the single nitrogen source. Required for binding of NrgB to the membrane. Interaction between GlnK-AmtB complex and TnrA protects TnrA from proteolytic degradation.
   
  
 0.917
yrpB
Putative anionic nitroalkane dioxygenase; Nitronate monooxygenase that uses molecular oxygen to catalyze the oxidative denitrification of alkyl nitronates. Acts on propionate 3-nitronate (P3N), the presumed physiological substrate. Probably functions in the detoxification of P3N, a metabolic poison produced by plants and fungi as a defense mechanism.
  
 
  0.907
Your Current Organism:
Bacillus subtilis 168
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
Server load: low (38%) [HD]