STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
bglCAryl-phospho-beta-d-glucosidase bglc; Is able to catalyze the hydrolysis of aryl-phospho-beta-D- glucosides such as 4-methylumbelliferyl-phospho-beta-D-glucopyranoside (MUG-P), phosphoarbutin and phosphosalicin. Is not essential for growth on arbutin and salicin as the sole carbon source (477 aa)    
Predicted Functional Partners:
glcK
Glucose kinase; Belongs to the ROK (NagC/XylR) family
   
 0.918
yugT
Putative oligo-1,6-glucosidase; Belongs to the glycosyl hydrolase 13 family
  
 
 0.907
sacA
sucrase-6-phosphate hydrolase; Belongs to the glycosyl hydrolase 32 family
     
 0.906
pgcA
Alpha-phosphoglucomutase; Catalyzes the interconversion between glucose-6-phosphate and alpha-glucose-1-phosphate. This is the first step in the biosynthesis of diglucosyl-diacylglycerol (Glc2-DAG), i.e. the predominant glycolipid found in B.subtilis membrane, which is also used as a membrane anchor for lipoteichoic acid (LTA). Has a role in the biosynthesis of all phosphate-containing envelope polymers, since glucose-1-phosphate is the precursor of UDP-glucose, which serves as a glucosyl donor not only for the biosynthesis of LTA but also for wall teichoic acids (WTAs). Is required fo [...]
     
 0.903
yxlE
Negative regulator of sigma-y activity; Together with YxlD is important for negative regulation of sigma Y activity
      
 0.902
yxlD
Putative sigma-y antisigma factor component; Together with YxlE, is important for negative regulation of sigma Y activity, being the major negative regulator
      
 0.902
pgi
Glucose-6-phosphate isomerase; Belongs to the GPI family
     
 0.900
sacB
Levansucrase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme
     
 0.900
xhlA
Defective prophage pbsx putative enzyme; Associated with cell lysis upon induction of PbsX
      
 0.881
gmuB
Pts system-oligo-beta-mannoside-specific transporter subunit iib; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II GmuABC PTS system is involved in the transport of oligo- glucomannans such as cellobiose or mannobiose
  
 
 0.818
Your Current Organism:
Bacillus subtilis
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
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