STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yclGUncharacterized protein YclG; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme (584 aa)    
Predicted Functional Partners:
ydaB
Putative acyl-coa ligase; Belongs to the ATP-dependent AMP-binding enzyme family
      
 0.810
ykzB
Uncharacterized protein YkzB; Evidence 5: No homology to any previously reported sequences; PubMedId: 10671441
      
 0.787
spoIIB
Stage ii sporulation protein b; Involved in endospore development
  
     0.781
ydaN
Uncharacterized protein YdaN; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: putative regulator
  
     0.779
epsK
Putative extracellular matrix component exporter; May be involved in the production of the exopolysaccharide (EPS) component of the extracellular matrix during biofilm formation. EPS is responsible for the adhesion of chains of cells into bundles
 
     0.779
ytrD
Acetoin utilization transport system permease protein; Part of the ABC transporter complex YtrBCDEF that plays a role in acetoin utilization during stationary phase and sporulation
  
     0.778
ytrC
Acetoin utilization transport system permease protein; Part of the ABC transporter complex YtrBCDEF that plays a role in acetoin utilization during stationary phase and sporulation
  
     0.773
rapA
Response regulator aspartate phosphatase a (stage 0 sporulation protein l); Prevents sporulation by dephosphorylating Spo0F
  
     0.766
cotO
Spore outer coat protein; Has an important morphogenetic role. Involved in the assembly of at least five coat proteins, including CotB, CotG, CotS, CotSA and CotW. Required for appearance of a morphologically normal outer coat. To a large degree, CotO and CotH act at a late stage of coat assembly from within the outer coat to direct maturation of this structure
  
     0.763
epsG
May be involved in the production of the exopolysaccharide (EPS) component of the extracellular matrix during biofilm formation. EPS is responsible for the adhesion of chains of cells into bundles. Required for biofilm maintenance
  
     0.759
Your Current Organism:
Bacillus subtilis
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
Server load: low (6%) [HD]