Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ycnCPutative transcriptional regulator (TetR/AcrR family); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: putative regulator. (292 aa)    
Predicted Functional Partners:
ycnB
Putative efflux transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
  
    0.922
yfiR
Transcriptional regulator (TetR/AcrR family); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type r: regulator.
   
  
 0.903
helD
DNA 3'-5' helicase IV; Catalyzes the unwinding of duplex DNA in the 3' to 5' direction; this reaction is dependent on the hydrolysis of ATP.
   
  
 0.712
rbsA
Ribose ABC transporter (ATP-binding protein); Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family.
      
 0.637
rbsD
Ribose ABC transporter (membrane bound ribose binding); Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
      
 0.634
qoxD
Cytochrome aa3-600 quinol oxidase (subunit IV); Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Major component for energy conversion during vegetative growth (By similarity).
  
     0.585
rbsB
Ribose ABC transporter (ribose-binding lipoprotein); Part of the ABC transporter complex RbsABC involved in ribose import. Binds ribose.
      
 0.572
ycnE
Conserved hypothetical protein; Putative monooxygenase that may contribute to the degradation of aromatic compounds; Belongs to the LsrG family.
  
    0.555
yozC
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
  
    0.546
nfrAB
NADPH-FMN oxidoreductase (nitroreductase); Reduces FMNH(2) to FMN, with NADH or NADPH as reductant. It also reduces nitroaromatic compounds, quinones, chromates and azo dyes. It could supply the reduced form of FMN to luciferase-like protein and contribute to the degradation of aromatic compounds. Belongs to the flavin oxidoreductase frp family.
  
    0.541
Your Current Organism:
Bacillus subtilis 168
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
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