| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| csoR | ycnI | BSU33520 | BSU03940 | Repressor of copper utilisation proteins; Copper-sensitive repressor that has a key role in copper homeostasis. Negatively regulates expression of the copZA operon and of ycnJ. In the absence of copper ions, binds with high affinity to the copZA promoter and represses the transcription. In the presence of copper ions, CsoR binds Cu(1+), which significantly decreases its DNA binding affinity and leads to the transcription of the genes. | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | 0.680 |
| csoR | ycnJ | BSU33520 | BSU03950 | Repressor of copper utilisation proteins; Copper-sensitive repressor that has a key role in copper homeostasis. Negatively regulates expression of the copZA operon and of ycnJ. In the absence of copper ions, binds with high affinity to the copZA promoter and represses the transcription. In the presence of copper ions, CsoR binds Cu(1+), which significantly decreases its DNA binding affinity and leads to the transcription of the genes. | Putative copper import protein; Involved in uptake of extracellular oxidized copper under copper-limiting conditions; In the N-terminal section; belongs to the CopC family. | 0.953 |
| csoR | ycnK | BSU33520 | BSU03960 | Repressor of copper utilisation proteins; Copper-sensitive repressor that has a key role in copper homeostasis. Negatively regulates expression of the copZA operon and of ycnJ. In the absence of copper ions, binds with high affinity to the copZA promoter and represses the transcription. In the presence of copper ions, CsoR binds Cu(1+), which significantly decreases its DNA binding affinity and leads to the transcription of the genes. | Putative transcriptional regulator (DeoR family); May act as a negative transcriptional regulator of ycnJ in the presence of copper. May use copper as a corepressor. | 0.847 |
| deoR | ycnI | BSU39430 | BSU03940 | Transcriptional regulator; Negative regulator of the dra-nupC-pdp operon. DeoR binds cooperatively to the operator DNA, which consists of a palindrome and a direct repeat sequence located 3' to the palindrome. Belongs to the SorC transcriptional regulatory family. | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | 0.632 |
| deoR | ycnJ | BSU39430 | BSU03950 | Transcriptional regulator; Negative regulator of the dra-nupC-pdp operon. DeoR binds cooperatively to the operator DNA, which consists of a palindrome and a direct repeat sequence located 3' to the palindrome. Belongs to the SorC transcriptional regulatory family. | Putative copper import protein; Involved in uptake of extracellular oxidized copper under copper-limiting conditions; In the N-terminal section; belongs to the CopC family. | 0.504 |
| deoR | ycnK | BSU39430 | BSU03960 | Transcriptional regulator; Negative regulator of the dra-nupC-pdp operon. DeoR binds cooperatively to the operator DNA, which consists of a palindrome and a direct repeat sequence located 3' to the palindrome. Belongs to the SorC transcriptional regulatory family. | Putative transcriptional regulator (DeoR family); May act as a negative transcriptional regulator of ycnJ in the presence of copper. May use copper as a corepressor. | 0.779 |
| deoR | ycnL | BSU39430 | BSU03970 | Transcriptional regulator; Negative regulator of the dra-nupC-pdp operon. DeoR binds cooperatively to the operator DNA, which consists of a palindrome and a direct repeat sequence located 3' to the palindrome. Belongs to the SorC transcriptional regulatory family. | Putative reductase or disulfide isomerase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme. | 0.631 |
| fruK | ycnK | BSU14390 | BSU03960 | Fructose-1-phosphate kinase; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme. | Putative transcriptional regulator (DeoR family); May act as a negative transcriptional regulator of ycnJ in the presence of copper. May use copper as a corepressor. | 0.595 |
| qdoR | ycnK | BSU39990 | BSU03960 | Transcriptional regulator; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type r: regulator. | Putative transcriptional regulator (DeoR family); May act as a negative transcriptional regulator of ycnJ in the presence of copper. May use copper as a corepressor. | 0.830 |
| qdoR | yetL | BSU39990 | BSU07220 | Transcriptional regulator; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type r: regulator. | Putative transcriptional regulator (MarR family); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: putative regulator. | 0.682 |
| ycnI | csoR | BSU03940 | BSU33520 | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | Repressor of copper utilisation proteins; Copper-sensitive repressor that has a key role in copper homeostasis. Negatively regulates expression of the copZA operon and of ycnJ. In the absence of copper ions, binds with high affinity to the copZA promoter and represses the transcription. In the presence of copper ions, CsoR binds Cu(1+), which significantly decreases its DNA binding affinity and leads to the transcription of the genes. | 0.680 |
| ycnI | deoR | BSU03940 | BSU39430 | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | Transcriptional regulator; Negative regulator of the dra-nupC-pdp operon. DeoR binds cooperatively to the operator DNA, which consists of a palindrome and a direct repeat sequence located 3' to the palindrome. Belongs to the SorC transcriptional regulatory family. | 0.632 |
| ycnI | ycnJ | BSU03940 | BSU03950 | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | Putative copper import protein; Involved in uptake of extracellular oxidized copper under copper-limiting conditions; In the N-terminal section; belongs to the CopC family. | 0.999 |
| ycnI | ycnK | BSU03940 | BSU03960 | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | Putative transcriptional regulator (DeoR family); May act as a negative transcriptional regulator of ycnJ in the presence of copper. May use copper as a corepressor. | 0.998 |
| ycnI | ycnL | BSU03940 | BSU03970 | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | Putative reductase or disulfide isomerase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme. | 0.861 |
| ycnI | yobA | BSU03940 | BSU18810 | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | Hypothetical protein; Evidence 5: No homology to any previously reported sequences. | 0.848 |
| ycnI | ytkA | BSU03940 | BSU30660 | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | Putative lipoprotein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp: lipoprotein. | 0.767 |
| ycnJ | csoR | BSU03950 | BSU33520 | Putative copper import protein; Involved in uptake of extracellular oxidized copper under copper-limiting conditions; In the N-terminal section; belongs to the CopC family. | Repressor of copper utilisation proteins; Copper-sensitive repressor that has a key role in copper homeostasis. Negatively regulates expression of the copZA operon and of ycnJ. In the absence of copper ions, binds with high affinity to the copZA promoter and represses the transcription. In the presence of copper ions, CsoR binds Cu(1+), which significantly decreases its DNA binding affinity and leads to the transcription of the genes. | 0.953 |
| ycnJ | deoR | BSU03950 | BSU39430 | Putative copper import protein; Involved in uptake of extracellular oxidized copper under copper-limiting conditions; In the N-terminal section; belongs to the CopC family. | Transcriptional regulator; Negative regulator of the dra-nupC-pdp operon. DeoR binds cooperatively to the operator DNA, which consists of a palindrome and a direct repeat sequence located 3' to the palindrome. Belongs to the SorC transcriptional regulatory family. | 0.504 |
| ycnJ | ycnI | BSU03950 | BSU03940 | Putative copper import protein; Involved in uptake of extracellular oxidized copper under copper-limiting conditions; In the N-terminal section; belongs to the CopC family. | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | 0.999 |
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