| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| kipA | kipI | BSU04090 | BSU04080 | Putative hydrolase subunit antagonist of KipI; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate. In addition, counteracts the inhibitory action of PxpB (KipI) on sporulation, by binding to PxpB and preventing its function as an inhibitor of kinase A. | Putative inhibitor of the autophosphorylation reaction of KinA; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate. In addition, is a potent inhibitor of the autophosphorylation reaction of kinase A (kinA) and its reverse reaction, but does not inhibit phosphate transfer to the Spo0F response regulator once kinase A is phosphorylated. Is an inhibitor of the catalytic domain of kinase A affecting the ATP/ADP reactions and not the phosphotransferase functions of this domain. The inhibition is non- competitive with re [...] | 0.999 |
| kipA | kipR | BSU04090 | BSU04100 | Putative hydrolase subunit antagonist of KipI; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate. In addition, counteracts the inhibitory action of PxpB (KipI) on sporulation, by binding to PxpB and preventing its function as an inhibitor of kinase A. | Transcriptional regulator (IclR family); Transcriptional repressor of the kip gene-containing operon. | 0.979 |
| kipA | lipC | BSU04090 | BSU04110 | Putative hydrolase subunit antagonist of KipI; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate. In addition, counteracts the inhibitory action of PxpB (KipI) on sporulation, by binding to PxpB and preventing its function as an inhibitor of kinase A. | Spore coat phospholipase B; Lipase involved in spore germination. Belongs to the 'GDSL' lipolytic enzyme family. | 0.849 |
| kipA | ycsF | BSU04090 | BSU04050 | Putative hydrolase subunit antagonist of KipI; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate. In addition, counteracts the inhibitory action of PxpB (KipI) on sporulation, by binding to PxpB and preventing its function as an inhibitor of kinase A. | Putative nitrogen-containing heterocycle degradation enzyme; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate. Belongs to the LamB/PxpA family. | 0.999 |
| kipA | ycsG | BSU04090 | BSU04060 | Putative hydrolase subunit antagonist of KipI; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate. In addition, counteracts the inhibitory action of PxpB (KipI) on sporulation, by binding to PxpB and preventing its function as an inhibitor of kinase A. | Putative branched chain amino acids transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter. | 0.992 |
| kipA | ycsI | BSU04090 | BSU04070 | Putative hydrolase subunit antagonist of KipI; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate. In addition, counteracts the inhibitory action of PxpB (KipI) on sporulation, by binding to PxpB and preventing its function as an inhibitor of kinase A. | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 9334321; Belongs to the D-glutamate cyclase family. | 0.943 |
| kipI | kipA | BSU04080 | BSU04090 | Putative inhibitor of the autophosphorylation reaction of KinA; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate. In addition, is a potent inhibitor of the autophosphorylation reaction of kinase A (kinA) and its reverse reaction, but does not inhibit phosphate transfer to the Spo0F response regulator once kinase A is phosphorylated. Is an inhibitor of the catalytic domain of kinase A affecting the ATP/ADP reactions and not the phosphotransferase functions of this domain. The inhibition is non- competitive with re [...] | Putative hydrolase subunit antagonist of KipI; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate. In addition, counteracts the inhibitory action of PxpB (KipI) on sporulation, by binding to PxpB and preventing its function as an inhibitor of kinase A. | 0.999 |
| kipI | kipR | BSU04080 | BSU04100 | Putative inhibitor of the autophosphorylation reaction of KinA; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate. In addition, is a potent inhibitor of the autophosphorylation reaction of kinase A (kinA) and its reverse reaction, but does not inhibit phosphate transfer to the Spo0F response regulator once kinase A is phosphorylated. Is an inhibitor of the catalytic domain of kinase A affecting the ATP/ADP reactions and not the phosphotransferase functions of this domain. The inhibition is non- competitive with re [...] | Transcriptional regulator (IclR family); Transcriptional repressor of the kip gene-containing operon. | 0.986 |
| kipI | lipC | BSU04080 | BSU04110 | Putative inhibitor of the autophosphorylation reaction of KinA; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate. In addition, is a potent inhibitor of the autophosphorylation reaction of kinase A (kinA) and its reverse reaction, but does not inhibit phosphate transfer to the Spo0F response regulator once kinase A is phosphorylated. Is an inhibitor of the catalytic domain of kinase A affecting the ATP/ADP reactions and not the phosphotransferase functions of this domain. The inhibition is non- competitive with re [...] | Spore coat phospholipase B; Lipase involved in spore germination. Belongs to the 'GDSL' lipolytic enzyme family. | 0.817 |
| kipI | ycsF | BSU04080 | BSU04050 | Putative inhibitor of the autophosphorylation reaction of KinA; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate. In addition, is a potent inhibitor of the autophosphorylation reaction of kinase A (kinA) and its reverse reaction, but does not inhibit phosphate transfer to the Spo0F response regulator once kinase A is phosphorylated. Is an inhibitor of the catalytic domain of kinase A affecting the ATP/ADP reactions and not the phosphotransferase functions of this domain. The inhibition is non- competitive with re [...] | Putative nitrogen-containing heterocycle degradation enzyme; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate. Belongs to the LamB/PxpA family. | 0.999 |
| kipI | ycsG | BSU04080 | BSU04060 | Putative inhibitor of the autophosphorylation reaction of KinA; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate. In addition, is a potent inhibitor of the autophosphorylation reaction of kinase A (kinA) and its reverse reaction, but does not inhibit phosphate transfer to the Spo0F response regulator once kinase A is phosphorylated. Is an inhibitor of the catalytic domain of kinase A affecting the ATP/ADP reactions and not the phosphotransferase functions of this domain. The inhibition is non- competitive with re [...] | Putative branched chain amino acids transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter. | 0.988 |
| kipI | ycsI | BSU04080 | BSU04070 | Putative inhibitor of the autophosphorylation reaction of KinA; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate. In addition, is a potent inhibitor of the autophosphorylation reaction of kinase A (kinA) and its reverse reaction, but does not inhibit phosphate transfer to the Spo0F response regulator once kinase A is phosphorylated. Is an inhibitor of the catalytic domain of kinase A affecting the ATP/ADP reactions and not the phosphotransferase functions of this domain. The inhibition is non- competitive with re [...] | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 9334321; Belongs to the D-glutamate cyclase family. | 0.975 |
| kipR | kipA | BSU04100 | BSU04090 | Transcriptional regulator (IclR family); Transcriptional repressor of the kip gene-containing operon. | Putative hydrolase subunit antagonist of KipI; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate. In addition, counteracts the inhibitory action of PxpB (KipI) on sporulation, by binding to PxpB and preventing its function as an inhibitor of kinase A. | 0.979 |
| kipR | kipI | BSU04100 | BSU04080 | Transcriptional regulator (IclR family); Transcriptional repressor of the kip gene-containing operon. | Putative inhibitor of the autophosphorylation reaction of KinA; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate. In addition, is a potent inhibitor of the autophosphorylation reaction of kinase A (kinA) and its reverse reaction, but does not inhibit phosphate transfer to the Spo0F response regulator once kinase A is phosphorylated. Is an inhibitor of the catalytic domain of kinase A affecting the ATP/ADP reactions and not the phosphotransferase functions of this domain. The inhibition is non- competitive with re [...] | 0.986 |
| kipR | lipC | BSU04100 | BSU04110 | Transcriptional regulator (IclR family); Transcriptional repressor of the kip gene-containing operon. | Spore coat phospholipase B; Lipase involved in spore germination. Belongs to the 'GDSL' lipolytic enzyme family. | 0.826 |
| kipR | ycbG | BSU04100 | BSU02500 | Transcriptional regulator (IclR family); Transcriptional repressor of the kip gene-containing operon. | Transcriptional regulator (GntR family); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type r: regulator. | 0.617 |
| kipR | ycsF | BSU04100 | BSU04050 | Transcriptional regulator (IclR family); Transcriptional repressor of the kip gene-containing operon. | Putative nitrogen-containing heterocycle degradation enzyme; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate. Belongs to the LamB/PxpA family. | 0.882 |
| kipR | ycsG | BSU04100 | BSU04060 | Transcriptional regulator (IclR family); Transcriptional repressor of the kip gene-containing operon. | Putative branched chain amino acids transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter. | 0.885 |
| kipR | ycsI | BSU04100 | BSU04070 | Transcriptional regulator (IclR family); Transcriptional repressor of the kip gene-containing operon. | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 9334321; Belongs to the D-glutamate cyclase family. | 0.916 |
| kipR | ygaB | BSU04100 | BSU08670 | Transcriptional regulator (IclR family); Transcriptional repressor of the kip gene-containing operon. | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | 0.745 |
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