node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
gsiB | ydaT | BSU04400 | BSU04380 | General stress protein; Involved in an adaptive response to nutrient deprivation other than sporulation. | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | 0.589 |
gsiB | ydbA | BSU04400 | BSU04390 | General stress protein; Involved in an adaptive response to nutrient deprivation other than sporulation. | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | 0.598 |
gsiB | ydbB | BSU04400 | BSU04410 | General stress protein; Involved in an adaptive response to nutrient deprivation other than sporulation. | Putative enzyme; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the SchB/CurC family. | 0.491 |
lrpC | topB | BSU04250 | BSU04260 | Transcriptional regulator (Lrp/AsnC family); Transcriptional regulator with a possible role in regulation of amino acid metabolism. Plays a role in the growth phase transition. | DNA topoisomerase III; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA su [...] | 0.805 |
lrpC | ydbA | BSU04250 | BSU04390 | Transcriptional regulator (Lrp/AsnC family); Transcriptional regulator with a possible role in regulation of amino acid metabolism. Plays a role in the growth phase transition. | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | 0.662 |
lrpC | ydzA | BSU04250 | BSU04240 | Transcriptional regulator (Lrp/AsnC family); Transcriptional regulator with a possible role in regulation of amino acid metabolism. Plays a role in the growth phase transition. | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | 0.728 |
nrnB | ydbA | BSU18200 | BSU04390 | Oligoribonuclease (nanoRNase); Degrades RNA oligonucleotides with a length of 5 nucleotides in a 3'- to 5'-direction. Less active on shorter RNA oligonucleotides and on those with a length of 24 nucleotides. Prefers RNA oligonucleotides containing adenines rather than cytosines. | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | 0.614 |
ppsC | ppsD | BSU18320 | BSU18310 | Plipastatin synthetase; This protein is a multifunctional enzyme, able to activate and polymerize the amino acids Glu and Ala/Val as part of the biosynthesis of the lipopeptide antibiotic plipastatin. The Ala/Val residue is further epimerized to the D-isomer form. The activation sites for these amino acids consist of individual domains. Belongs to the ATP-dependent AMP-binding enzyme family. | Plipastatin synthetase; This protein is a multifunctional enzyme, able to activate and polymerize the amino acids Pro, Gln and Tyr as part of the biosynthesis of the lipopeptide antibiotic plipastatin. The Tyr residue is further epimerized to the D-isomer form. The activation sites for these amino acids consist of individual domains. Belongs to the ATP-dependent AMP-binding enzyme family. | 0.825 |
ppsC | ydbA | BSU18320 | BSU04390 | Plipastatin synthetase; This protein is a multifunctional enzyme, able to activate and polymerize the amino acids Glu and Ala/Val as part of the biosynthesis of the lipopeptide antibiotic plipastatin. The Ala/Val residue is further epimerized to the D-isomer form. The activation sites for these amino acids consist of individual domains. Belongs to the ATP-dependent AMP-binding enzyme family. | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | 0.680 |
ppsC | ydzA | BSU18320 | BSU04240 | Plipastatin synthetase; This protein is a multifunctional enzyme, able to activate and polymerize the amino acids Glu and Ala/Val as part of the biosynthesis of the lipopeptide antibiotic plipastatin. The Ala/Val residue is further epimerized to the D-isomer form. The activation sites for these amino acids consist of individual domains. Belongs to the ATP-dependent AMP-binding enzyme family. | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | 0.482 |
ppsD | ppsC | BSU18310 | BSU18320 | Plipastatin synthetase; This protein is a multifunctional enzyme, able to activate and polymerize the amino acids Pro, Gln and Tyr as part of the biosynthesis of the lipopeptide antibiotic plipastatin. The Tyr residue is further epimerized to the D-isomer form. The activation sites for these amino acids consist of individual domains. Belongs to the ATP-dependent AMP-binding enzyme family. | Plipastatin synthetase; This protein is a multifunctional enzyme, able to activate and polymerize the amino acids Glu and Ala/Val as part of the biosynthesis of the lipopeptide antibiotic plipastatin. The Ala/Val residue is further epimerized to the D-isomer form. The activation sites for these amino acids consist of individual domains. Belongs to the ATP-dependent AMP-binding enzyme family. | 0.825 |
ppsD | ydbA | BSU18310 | BSU04390 | Plipastatin synthetase; This protein is a multifunctional enzyme, able to activate and polymerize the amino acids Pro, Gln and Tyr as part of the biosynthesis of the lipopeptide antibiotic plipastatin. The Tyr residue is further epimerized to the D-isomer form. The activation sites for these amino acids consist of individual domains. Belongs to the ATP-dependent AMP-binding enzyme family. | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | 0.681 |
ppsD | ydzA | BSU18310 | BSU04240 | Plipastatin synthetase; This protein is a multifunctional enzyme, able to activate and polymerize the amino acids Pro, Gln and Tyr as part of the biosynthesis of the lipopeptide antibiotic plipastatin. The Tyr residue is further epimerized to the D-isomer form. The activation sites for these amino acids consist of individual domains. Belongs to the ATP-dependent AMP-binding enzyme family. | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | 0.483 |
topB | lrpC | BSU04260 | BSU04250 | DNA topoisomerase III; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA su [...] | Transcriptional regulator (Lrp/AsnC family); Transcriptional regulator with a possible role in regulation of amino acid metabolism. Plays a role in the growth phase transition. | 0.805 |
topB | ydbA | BSU04260 | BSU04390 | DNA topoisomerase III; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA su [...] | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | 0.711 |
topB | ydzA | BSU04260 | BSU04240 | DNA topoisomerase III; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA su [...] | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | 0.696 |
ydaT | gsiB | BSU04380 | BSU04400 | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | General stress protein; Involved in an adaptive response to nutrient deprivation other than sporulation. | 0.589 |
ydaT | ydbA | BSU04380 | BSU04390 | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | 0.538 |
ydbA | gsiB | BSU04390 | BSU04400 | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | General stress protein; Involved in an adaptive response to nutrient deprivation other than sporulation. | 0.598 |
ydbA | lrpC | BSU04390 | BSU04250 | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | Transcriptional regulator (Lrp/AsnC family); Transcriptional regulator with a possible role in regulation of amino acid metabolism. Plays a role in the growth phase transition. | 0.662 |