node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ctpA | ydfJ | BSU19590 | BSU05430 | Carboxy-terminal processing protease; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Putative proton metabolite efflux transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MmpL subfamily. | 0.578 |
ctpA | ytxK | BSU19590 | BSU29480 | Carboxy-terminal processing protease; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Putative nucleic acid methyltransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; To type I restriction system adenine methylases. | 0.753 |
epsJ | ydfJ | BSU34280 | BSU05430 | Putative glycosyl transferase; May be involved in the production of the exopolysaccharide (EPS) component of the extracellular matrix during biofilm formation. EPS is responsible for the adhesion of chains of cells into bundles; Belongs to the glycosyltransferase 2 family. | Putative proton metabolite efflux transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MmpL subfamily. | 0.681 |
epsJ | yhaI | BSU34280 | BSU09980 | Putative glycosyl transferase; May be involved in the production of the exopolysaccharide (EPS) component of the extracellular matrix during biofilm formation. EPS is responsible for the adhesion of chains of cells into bundles; Belongs to the glycosyltransferase 2 family. | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | 0.429 |
epsJ | ytxK | BSU34280 | BSU29480 | Putative glycosyl transferase; May be involved in the production of the exopolysaccharide (EPS) component of the extracellular matrix during biofilm formation. EPS is responsible for the adhesion of chains of cells into bundles; Belongs to the glycosyltransferase 2 family. | Putative nucleic acid methyltransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; To type I restriction system adenine methylases. | 0.825 |
glnQ | ydfJ | BSU27430 | BSU05430 | Glutamine ABC transporter (ATP-binding protein); Part of the ABC transporter complex GlnHMPQ involved in glutamine transport. Probably responsible for energy coupling to the transport system (By similarity). | Putative proton metabolite efflux transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MmpL subfamily. | 0.681 |
tgt | trmB | BSU27710 | BSU29900 | tRNA-guanine transglycosylase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the [...] | tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family. | 0.831 |
tgt | ydfJ | BSU27710 | BSU05430 | tRNA-guanine transglycosylase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the [...] | Putative proton metabolite efflux transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MmpL subfamily. | 0.486 |
trmB | tgt | BSU29900 | BSU27710 | tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family. | tRNA-guanine transglycosylase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the [...] | 0.831 |
trmB | ydfJ | BSU29900 | BSU05430 | tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family. | Putative proton metabolite efflux transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MmpL subfamily. | 0.674 |
ydfH | ydfI | BSU05410 | BSU05420 | Two-component sensor histidine kinase [YdfI]; Member of the two-component regulatory system YdfH/YdfI. May activate YdfI by phosphorylation. | Two-component response regulator [YdfH]; Member of the two-component regulatory system YdfH/YdfI. Regulates the transcription of ydfJ by binding to its promoter region. | 0.997 |
ydfH | ydfJ | BSU05410 | BSU05430 | Two-component sensor histidine kinase [YdfI]; Member of the two-component regulatory system YdfH/YdfI. May activate YdfI by phosphorylation. | Putative proton metabolite efflux transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MmpL subfamily. | 0.526 |
ydfI | ydfH | BSU05420 | BSU05410 | Two-component response regulator [YdfH]; Member of the two-component regulatory system YdfH/YdfI. Regulates the transcription of ydfJ by binding to its promoter region. | Two-component sensor histidine kinase [YdfI]; Member of the two-component regulatory system YdfH/YdfI. May activate YdfI by phosphorylation. | 0.997 |
ydfI | ydfJ | BSU05420 | BSU05430 | Two-component response regulator [YdfH]; Member of the two-component regulatory system YdfH/YdfI. Regulates the transcription of ydfJ by binding to its promoter region. | Putative proton metabolite efflux transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MmpL subfamily. | 0.923 |
ydfI | ydgH | BSU05420 | BSU05650 | Two-component response regulator [YdfH]; Member of the two-component regulatory system YdfH/YdfI. Regulates the transcription of ydfJ by binding to its promoter region. | Putative membrane component; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative membrane component; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MmpL subfamily. | 0.852 |
ydfJ | ctpA | BSU05430 | BSU19590 | Putative proton metabolite efflux transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MmpL subfamily. | Carboxy-terminal processing protease; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.578 |
ydfJ | epsJ | BSU05430 | BSU34280 | Putative proton metabolite efflux transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MmpL subfamily. | Putative glycosyl transferase; May be involved in the production of the exopolysaccharide (EPS) component of the extracellular matrix during biofilm formation. EPS is responsible for the adhesion of chains of cells into bundles; Belongs to the glycosyltransferase 2 family. | 0.681 |
ydfJ | glnQ | BSU05430 | BSU27430 | Putative proton metabolite efflux transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MmpL subfamily. | Glutamine ABC transporter (ATP-binding protein); Part of the ABC transporter complex GlnHMPQ involved in glutamine transport. Probably responsible for energy coupling to the transport system (By similarity). | 0.681 |
ydfJ | tgt | BSU05430 | BSU27710 | Putative proton metabolite efflux transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MmpL subfamily. | tRNA-guanine transglycosylase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the [...] | 0.486 |
ydfJ | trmB | BSU05430 | BSU29900 | Putative proton metabolite efflux transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MmpL subfamily. | tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family. | 0.674 |