STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gmuFMannose-6-phosphate isomerase GmuF; Seems to be involved in the degradation of glucomannan (315 aa)    
Predicted Functional Partners:
gmuE
Rok fructokinase; Seems to be involved in the degradation of glucomannan
  
 0.992
ydjE
Putative sugar kinase (ribokinase family); Belongs to the carbohydrate kinase PfkB family
   
 
 0.972
pgi
Glucose-6-phosphate isomerase; Belongs to the GPI family
 
 
 0.959
fbp
Fructose-1,6-bisphosphatase class 3; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme
  
  
 0.920
glmS
Glutamine---fructose-6-phosphate transaminase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
   
 
 0.918
mtlD
Mannitol-1-phosphate 5-dehydrogenase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme
    
 0.918
nagBB
Glucosamine-6-phosphate deaminase 2; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
     
 0.914
nagBA
N-acetylglucosamine-6-phosphate isomerase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
     
 0.914
ybcM
Glutamine---fructose-6-phosphate transaminase (isomerizing); Uncharacterized protein YbcM; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme
   
 
 0.912
pfkA
6-phosphofructokinase 1; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
  
 
 0.911
Your Current Organism:
Bacillus subtilis
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
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