STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
bsuRBType-2 restriction enzyme BsuMI component BsuRB (YdiS); Recognizes the double-stranded sequence CTCGAG; the cleavage site is unknown. (343 aa)    
Predicted Functional Partners:
bsuRC
Type-2 restriction enzyme BsuMI component BsuRC (YdjA); Recognizes the double-stranded sequence CTCGAG; the cleavage site is unknown.
  
  
 0.991
bsuRA
Putative phosphomannomutase; Recognizes the double-stranded sequence CTCGAG; the cleavage site is unknown.
  
  
 0.988
bsuMB
DNA-methyltransferase (cytosine-specific); This methylase may recognize the double-stranded sequence CTCGAG, causing specific methylation on C-? on both strands, and protects the DNA from cleavage by the BsuMI endonuclease. Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
  
  
 0.900
bsuMA
Conserved hypothetical protein; This methylase may recognize the double-stranded sequence CTCGAG, causing specific methylation on C-? on both strands, and protects the DNA from cleavage by the BsuMI endonuclease. Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
 
  
 0.896
yqaE
Putative transcriptional regulator (Xre family); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: putative regulator.
      
 0.689
yezG
Conserved hypothetical protein; Probable antitoxin component of a type II toxin-antitoxin (TA) system. Probably neutralizes the ability to inhibit growth of cognate toxin YeeF. Probably does not have antitoxin activity on other toxins with the LXG toxin domain (Probable).
      
 0.573
rttF
Antitoxin factor of ribonuclease toxin RttG; Antitoxin component of a type II toxin-antitoxin (TA) system. Neutralizes the RNase activity of cognate toxin YqcG, as well as its ability to inhibit growth upon expression in E.coli. Does not have antitoxin activity on other toxins with the LXG toxin domain.
   
  
 0.565
rtbE
Antitoxin factor of the RttD-RttE toxin-antitoxin system; Antitoxin component of a type II toxin-antitoxin (TA) system. Neutralizes the RNase activity of cognate toxin YxiD, as well as its ability to inhibit growth upon expression in E.coli. Does not have antitoxin activity on other toxins with the LXG toxin domain.
   
  
 0.565
ylaN
Conserved hypothetical protein; Essential for cell growth and for normal cell shape.
      
 0.483
yxxG
Hypothetical protein; Immunity protein component of a toxin-immunity protein module, which functions as a cellular contact-dependent growth inhibition (CDI) system. Neutralizes the tRNase activity of cognate toxin WapA upon expression in E.coli. Does not inhibit WapA from other strains of B.subtilis. The WapA C-terminus cannot be expressed on its own in E.coli, however it can be cloned in the presence of its cognate immunity protein gene. Cell contact is necessary for growth inhibition.
   
  
 0.483
Your Current Organism:
Bacillus subtilis 168
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
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