node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
alaS | gutR | BSU27410 | BSU06140 | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. | Transcriptional regulator of the glucitol operon; Activator of the glucitol dehydrogenase gene (gutB). | 0.540 |
gutB | gutR | BSU06150 | BSU06140 | Glucitol (sorbitol) dehydrogenase; Polyol dehydrogenase that catalyzes the NAD(+)-dependent oxidation of various sugar alcohols. Is mostly active with D-sorbitol (D-glucitol), xylitol and L-iditol as substrates, leading to the C2- oxidized products D-fructose, D-xylulose and L-sorbose, respectively. | Transcriptional regulator of the glucitol operon; Activator of the glucitol dehydrogenase gene (gutB). | 0.938 |
gutB | ydjE | BSU06150 | BSU06170 | Glucitol (sorbitol) dehydrogenase; Polyol dehydrogenase that catalyzes the NAD(+)-dependent oxidation of various sugar alcohols. Is mostly active with D-sorbitol (D-glucitol), xylitol and L-iditol as substrates, leading to the C2- oxidized products D-fructose, D-xylulose and L-sorbose, respectively. | Putative sugar kinase (ribokinase family); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the carbohydrate kinase PfkB family. | 0.984 |
gutR | alaS | BSU06140 | BSU27410 | Transcriptional regulator of the glucitol operon; Activator of the glucitol dehydrogenase gene (gutB). | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. | 0.540 |
gutR | gutB | BSU06140 | BSU06150 | Transcriptional regulator of the glucitol operon; Activator of the glucitol dehydrogenase gene (gutB). | Glucitol (sorbitol) dehydrogenase; Polyol dehydrogenase that catalyzes the NAD(+)-dependent oxidation of various sugar alcohols. Is mostly active with D-sorbitol (D-glucitol), xylitol and L-iditol as substrates, leading to the C2- oxidized products D-fructose, D-xylulose and L-sorbose, respectively. | 0.938 |
gutR | htpG | BSU06140 | BSU39820 | Transcriptional regulator of the glucitol operon; Activator of the glucitol dehydrogenase gene (gutB). | Class III heat-shock protein (molecular chaperone); Molecular chaperone. Has ATPase activity. | 0.569 |
gutR | rhaD | BSU06140 | BSU31220 | Transcriptional regulator of the glucitol operon; Activator of the glucitol dehydrogenase gene (gutB). | Putative Bifunctional rhamnulose-1-phosphate aldolase/alcohol dehydrogenase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.741 |
gutR | ydjE | BSU06140 | BSU06170 | Transcriptional regulator of the glucitol operon; Activator of the glucitol dehydrogenase gene (gutB). | Putative sugar kinase (ribokinase family); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the carbohydrate kinase PfkB family. | 0.680 |
gutR | yhcY | BSU06140 | BSU09320 | Transcriptional regulator of the glucitol operon; Activator of the glucitol dehydrogenase gene (gutB). | Two-component sensor histidine kinase [YhcZ]; Member of the two-component regulatory system YhcY/YhcZ. Probably activates YhcZ by phosphorylation. | 0.799 |
gutR | yhcZ | BSU06140 | BSU09330 | Transcriptional regulator of the glucitol operon; Activator of the glucitol dehydrogenase gene (gutB). | Two-component response regulator [YhcY]; Member of the two-component regulatory system YhcY/YhcZ. | 0.754 |
gutR | yisJ | BSU06140 | BSU10740 | Transcriptional regulator of the glucitol operon; Activator of the glucitol dehydrogenase gene (gutB). | Putative spore coat protein; Involved in the assembly of several proteins in the inner and outer layer of the spore coat; Belongs to the CotH family. | 0.624 |
gutR | yobD | BSU06140 | BSU18850 | Transcriptional regulator of the glucitol operon; Activator of the glucitol dehydrogenase gene (gutB). | Transcriptional regulator (phage-related, Xre family); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type h: extrachromosomal origin. | 0.830 |
gutR | yxeL | BSU06140 | BSU39510 | Transcriptional regulator of the glucitol operon; Activator of the glucitol dehydrogenase gene (gutB). | Putative acetyltransferase; Catalyzes the N-acetylation of S-(2-succino)cysteine. Is involved in a S-(2-succino)cysteine (2SC) degradation pathway that allows B.subtilis to grow on 2SC as a sole sulfur source, via its metabolization to cysteine. Moreover, 2SC is a toxic compound in B.subtilis at high exogenous concentrations, and this enzyme relieves 2SC toxicity via N-acetylation; Belongs to the acetyltransferase family. | 0.567 |
htpG | gutR | BSU39820 | BSU06140 | Class III heat-shock protein (molecular chaperone); Molecular chaperone. Has ATPase activity. | Transcriptional regulator of the glucitol operon; Activator of the glucitol dehydrogenase gene (gutB). | 0.569 |
rhaD | gutR | BSU31220 | BSU06140 | Putative Bifunctional rhamnulose-1-phosphate aldolase/alcohol dehydrogenase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | Transcriptional regulator of the glucitol operon; Activator of the glucitol dehydrogenase gene (gutB). | 0.741 |
rhaD | ydjE | BSU31220 | BSU06170 | Putative Bifunctional rhamnulose-1-phosphate aldolase/alcohol dehydrogenase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | Putative sugar kinase (ribokinase family); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the carbohydrate kinase PfkB family. | 0.711 |
ydjE | gutB | BSU06170 | BSU06150 | Putative sugar kinase (ribokinase family); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the carbohydrate kinase PfkB family. | Glucitol (sorbitol) dehydrogenase; Polyol dehydrogenase that catalyzes the NAD(+)-dependent oxidation of various sugar alcohols. Is mostly active with D-sorbitol (D-glucitol), xylitol and L-iditol as substrates, leading to the C2- oxidized products D-fructose, D-xylulose and L-sorbose, respectively. | 0.984 |
ydjE | gutR | BSU06170 | BSU06140 | Putative sugar kinase (ribokinase family); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the carbohydrate kinase PfkB family. | Transcriptional regulator of the glucitol operon; Activator of the glucitol dehydrogenase gene (gutB). | 0.680 |
ydjE | rhaD | BSU06170 | BSU31220 | Putative sugar kinase (ribokinase family); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the carbohydrate kinase PfkB family. | Putative Bifunctional rhamnulose-1-phosphate aldolase/alcohol dehydrogenase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.711 |
yhcY | gutR | BSU09320 | BSU06140 | Two-component sensor histidine kinase [YhcZ]; Member of the two-component regulatory system YhcY/YhcZ. Probably activates YhcZ by phosphorylation. | Transcriptional regulator of the glucitol operon; Activator of the glucitol dehydrogenase gene (gutB). | 0.799 |