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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
co-expression
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gene co-occurrence
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[Homology]
Score
ydjEPutative sugar kinase (ribokinase family); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the carbohydrate kinase PfkB family. (320 aa)    
Predicted Functional Partners:
sacA
Sucrase-6-phosphate hydrolase; Evidence 2b: Function of strongly homologous gene; Product type e: enzyme; Belongs to the glycosyl hydrolase 32 family.
 
 0.994
gutB
Glucitol (sorbitol) dehydrogenase; Polyol dehydrogenase that catalyzes the NAD(+)-dependent oxidation of various sugar alcohols. Is mostly active with D-sorbitol (D-glucitol), xylitol and L-iditol as substrates, leading to the C2- oxidized products D-fructose, D-xylulose and L-sorbose, respectively.
  
 
 0.973
sacC
Levanase; Exo-fructosidase that can hydrolyze both levan and inulin, leading to the production of free fructose. Is also able to hydrolyze sucrose and to a small extent raffinose, but not melezitose, stachylose, cellobiose, maltose, and lactose.
 
 0.969
fruA
Phosphotransferase system (PTS) fructose-specific enzyme IIABC component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in fructose transport.
    
 0.965
gutP
H+-glucitol symporter; Probably involved in glucitol uptake; Belongs to the sodium:galactoside symporter (TC 2.A.2) family.
 
  
 0.964
levD
Phosphotransferase system (PTS) fructose-specific enzyme IIA component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II LevDE PTS system is involved in fructose transport.
  
 
 0.940
gmuF
Phosphohexomutase; Seems to be involved in the degradation of glucomannan. Belongs to the mannose-6-phosphate isomerase type 1 family.
    
 0.932
gutR
Transcriptional regulator of the glucitol operon; Activator of the glucitol dehydrogenase gene (gutB).
  
  
 0.929
pfkA
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub- subfamily.
  
 0.929
yvyI
Putative phosphohexomutase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type e: enzyme; Belongs to the mannose-6-phosphate isomerase type 1 family.
  
 
 0.921
Your Current Organism:
Bacillus subtilis 168
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
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