node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
liaG | liaI | BSU33110 | BSU33130 | Conserved hypothetical protein (response to antibiotic stress); Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15273097, 16816187. | Permease; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type t: transporter. | 0.990 |
liaG | liaR | BSU33110 | BSU33080 | Conserved hypothetical protein (response to antibiotic stress); Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15273097, 16816187. | Two-component response regulator [YvqE] responding to cell wall stress; Member of the two-component regulatory system LiaS/LiaR probably involved in response to a subset of cell wall-active antibiotics that interfere with the lipid II cycle in the cytoplasmic membrane (bacitracin, nisin, ramoplanin and vancomycin). Seems also involved in response to cationic antimicrobial peptides and secretion stress. LiaR regulates the transcription of the liaIHGFSR operon. | 0.992 |
liaG | liaS | BSU33110 | BSU33090 | Conserved hypothetical protein (response to antibiotic stress); Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15273097, 16816187. | Two-component sensor histidine kinase [YvqC] sensing cell wall stress; Member of the two-component regulatory system LiaS/LiaR probably involved in response to a subset of cell wall-active antibiotics that interfere with the lipid II cycle in the cytoplasmic membrane (bacitracin, nisin, ramoplanin and vancomycin). Seems also involved in response to cationic antimicrobial peptides and secretion stress. Activates probably LiaR by phosphorylation. | 0.997 |
liaG | pspA | BSU33110 | BSU06180 | Conserved hypothetical protein (response to antibiotic stress); Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15273097, 16816187. | Phage shock protein A homolog; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type h: extrachromosomal origin. | 0.741 |
liaG | ydjG | BSU33110 | BSU06190 | Conserved hypothetical protein (response to antibiotic stress); Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15273097, 16816187. | Putative phage replication protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin. | 0.836 |
liaG | ydjH | BSU33110 | BSU06200 | Conserved hypothetical protein (response to antibiotic stress); Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15273097, 16816187. | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | 0.849 |
liaG | ydjI | BSU33110 | BSU06210 | Conserved hypothetical protein (response to antibiotic stress); Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15273097, 16816187. | Putative phage protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin. | 0.848 |
liaG | yvlC | BSU33110 | BSU35110 | Conserved hypothetical protein (response to antibiotic stress); Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15273097, 16816187. | Putative regulator (stress mediated); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: putative regulator. | 0.448 |
liaI | liaG | BSU33130 | BSU33110 | Permease; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type t: transporter. | Conserved hypothetical protein (response to antibiotic stress); Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15273097, 16816187. | 0.990 |
liaI | liaR | BSU33130 | BSU33080 | Permease; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type t: transporter. | Two-component response regulator [YvqE] responding to cell wall stress; Member of the two-component regulatory system LiaS/LiaR probably involved in response to a subset of cell wall-active antibiotics that interfere with the lipid II cycle in the cytoplasmic membrane (bacitracin, nisin, ramoplanin and vancomycin). Seems also involved in response to cationic antimicrobial peptides and secretion stress. LiaR regulates the transcription of the liaIHGFSR operon. | 0.977 |
liaI | liaS | BSU33130 | BSU33090 | Permease; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type t: transporter. | Two-component sensor histidine kinase [YvqC] sensing cell wall stress; Member of the two-component regulatory system LiaS/LiaR probably involved in response to a subset of cell wall-active antibiotics that interfere with the lipid II cycle in the cytoplasmic membrane (bacitracin, nisin, ramoplanin and vancomycin). Seems also involved in response to cationic antimicrobial peptides and secretion stress. Activates probably LiaR by phosphorylation. | 0.959 |
liaI | pspA | BSU33130 | BSU06180 | Permease; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type t: transporter. | Phage shock protein A homolog; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type h: extrachromosomal origin. | 0.915 |
liaI | ydjG | BSU33130 | BSU06190 | Permease; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type t: transporter. | Putative phage replication protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin. | 0.682 |
liaI | ydjH | BSU33130 | BSU06200 | Permease; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type t: transporter. | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | 0.751 |
liaI | ydjI | BSU33130 | BSU06210 | Permease; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type t: transporter. | Putative phage protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin. | 0.746 |
liaR | liaG | BSU33080 | BSU33110 | Two-component response regulator [YvqE] responding to cell wall stress; Member of the two-component regulatory system LiaS/LiaR probably involved in response to a subset of cell wall-active antibiotics that interfere with the lipid II cycle in the cytoplasmic membrane (bacitracin, nisin, ramoplanin and vancomycin). Seems also involved in response to cationic antimicrobial peptides and secretion stress. LiaR regulates the transcription of the liaIHGFSR operon. | Conserved hypothetical protein (response to antibiotic stress); Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15273097, 16816187. | 0.992 |
liaR | liaI | BSU33080 | BSU33130 | Two-component response regulator [YvqE] responding to cell wall stress; Member of the two-component regulatory system LiaS/LiaR probably involved in response to a subset of cell wall-active antibiotics that interfere with the lipid II cycle in the cytoplasmic membrane (bacitracin, nisin, ramoplanin and vancomycin). Seems also involved in response to cationic antimicrobial peptides and secretion stress. LiaR regulates the transcription of the liaIHGFSR operon. | Permease; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type t: transporter. | 0.977 |
liaR | liaS | BSU33080 | BSU33090 | Two-component response regulator [YvqE] responding to cell wall stress; Member of the two-component regulatory system LiaS/LiaR probably involved in response to a subset of cell wall-active antibiotics that interfere with the lipid II cycle in the cytoplasmic membrane (bacitracin, nisin, ramoplanin and vancomycin). Seems also involved in response to cationic antimicrobial peptides and secretion stress. LiaR regulates the transcription of the liaIHGFSR operon. | Two-component sensor histidine kinase [YvqC] sensing cell wall stress; Member of the two-component regulatory system LiaS/LiaR probably involved in response to a subset of cell wall-active antibiotics that interfere with the lipid II cycle in the cytoplasmic membrane (bacitracin, nisin, ramoplanin and vancomycin). Seems also involved in response to cationic antimicrobial peptides and secretion stress. Activates probably LiaR by phosphorylation. | 0.999 |
liaR | pspA | BSU33080 | BSU06180 | Two-component response regulator [YvqE] responding to cell wall stress; Member of the two-component regulatory system LiaS/LiaR probably involved in response to a subset of cell wall-active antibiotics that interfere with the lipid II cycle in the cytoplasmic membrane (bacitracin, nisin, ramoplanin and vancomycin). Seems also involved in response to cationic antimicrobial peptides and secretion stress. LiaR regulates the transcription of the liaIHGFSR operon. | Phage shock protein A homolog; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type h: extrachromosomal origin. | 0.711 |
liaR | yvlB | BSU33080 | BSU35120 | Two-component response regulator [YvqE] responding to cell wall stress; Member of the two-component regulatory system LiaS/LiaR probably involved in response to a subset of cell wall-active antibiotics that interfere with the lipid II cycle in the cytoplasmic membrane (bacitracin, nisin, ramoplanin and vancomycin). Seems also involved in response to cationic antimicrobial peptides and secretion stress. LiaR regulates the transcription of the liaIHGFSR operon. | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | 0.531 |