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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ydjIPutative phage protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin. (323 aa)    
Predicted Functional Partners:
ydjG
Putative phage replication protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin.
 
  
 0.998
ydjH
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
 
  
 0.998
pspA
Phage shock protein A homolog; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type h: extrachromosomal origin.
 
  
 0.979
liaG
Conserved hypothetical protein (response to antibiotic stress); Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15273097, 16816187.
      
 0.848
liaI
Permease; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type t: transporter.
      
 0.746
dynA
Dynamin-like GTPase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme.
      
 0.687
liaH
Modulator of liaIHGFSR (yvqIHGFEC) operon expression; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type f: factor.
     
 0.592
ccpA
Transcriptional regulator (Lacl family); Global transcriptional regulator of carbon catabolite repression (CCR) and carbon catabolite activation (CCA), which ensures optimal energy usage under diverse conditions. Interacts with either P- Ser-HPr or P-Ser-Crh, leading to the formation of a complex that binds to DNA at the catabolite-response elements (cre). Binding to DNA allows activation or repression of many different genes and operons.
    
   0.570
yoaG
Putative permease; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane component.
   
    0.503
mreBH
Cell-shape determining protein; Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreBH localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature (By similarity). Filaments rotate around the cell circumference in concert with the cell wall synthesis enzymes. The process is driven by the cell wall synthesis machinery and does not depend on MreBH polymerization. O [...]
   
  
 0.434
Your Current Organism:
Bacillus subtilis 168
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
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